Journal ArticleDOI
Histopathology of Trypanosoma (Trypanozoon) evansi infection in bandicoot rat. I. visceral organs.
TLDR
The histopathological changes in these organs are compared with those studied in surra, human sleeping sickness disease, and African trypanosomiasis and possible mechanisms for these histologically changes in the visceral organs are discussed.About:
This article is published in Experimental Parasitology.The article was published on 2001-11-01. It has received 63 citations till now. The article focuses on the topics: Trypanosoma evansi & Lung.read more
Citations
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Journal ArticleDOI
Global metabolic responses of mice to Trypanosoma brucei brucei infection.
Yulan Wang,Jürg Utzinger,Jasmina Saric,Jia V. Li,Jean Burckhardt,Stephan Dirnhofer,Jeremy K. Nicholson,Burton H. Singer,Reto Brun,Elaine Holmes +9 more
TL;DR: Concluding, parasite infection results in multiple systemic biochemical effects in the host and disturbance of the symbiotic gut microbial metabolic interactions, which may underpin the development of new diagnostic criteria and metrics of therapeutic efficacy.
Journal ArticleDOI
Oligopeptidase B from Trypanosoma evansi A PARASITE PEPTIDASE THAT INACTIVATES ATRIAL NATRIURETIC FACTOR IN THE BLOODSTREAM OF INFECTED HOSTS
TL;DR: A role is proposed for OpdB in peptide hormone dysregulation in trypanosomiasis, specifically in generating the depressed plasma levels of ANF in mammals infected with T. evansi.
Journal ArticleDOI
Experimental Trypanosoma evansi infection in the goat. II. Pathology.
TL;DR: The findings indicated immunosuppression in the lymph nodes, spleen and bone marrow during the third month after infection, suggesting that the cytopathology of most haemophilic trypanosomal infections is predominantly an immunological process.
Journal ArticleDOI
Trypanosoma evansi in inbred and Swiss-Webster mice: distinct aspects of pathogenesis
Valquíria Trajano de Menezes,Adriana Oliveira Queiroz,Maria Angélica Muniz Gomes,Marcos Antônio Pereira Marques,Ana Maria Jansen +4 more
TL;DR: The results showed that T. evansi isolates displayed significant differences regarding behavior and morbidity patterns in the distinct mouse lineages, and showed that Mus musculus is a suitable model host for the study of the different pathogenetic features of T.evansi infection.
Journal ArticleDOI
Parasitic Pneumonia and Lung Involvement
TL;DR: A comprehensive review of both protozoal and helminthic infestations that affect the airway system, particularly the lungs, including clinical and roentgenographic presentations, diagnostic tests, and therapeutic approaches is provided.
References
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Journal ArticleDOI
Review of Pathology of Diseases in Domestic and Laboratory Animals Caused by Trypanosoma congolense, T. vivax, T. brucei, T. rhodesiense and T. gambiense:
G. J. Losos,B. O. Ikede +1 more
Journal Article
Suppressor macrophages in African trypanosomiasis inhibit T cell proliferative responses by nitric oxide and prostaglandins.
K W Schleifer,J M Mansfield +1 more
TL;DR: It is concluded that macrophage activation in trypanosomiasis induces the release of reactive nitrogen intermediates and PG, which down-regulate proliferative responses by T cells during infection.