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Horsfiline, an oxindole alkaloid from Horsfieldia superba

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This article is published in Journal of Organic Chemistry.The article was published on 1991-11-01. It has received 351 citations till now. The article focuses on the topics: Horsfiline & Horsfieldia superba.

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Highly Efficient Synthesis of Spirooxindole, Spiroacenaphthylene and Bisbenzo[b]pyran Derivatives and Evaluation of Their Inhibitory Activity against Sirtuin 2

TL;DR: In this article, an operationally simple and high yielding procedure for the synthesis of spirooxindole and spiroacenaphthylene derivatives is described by the condensation reaction between isatin/acenAPHthenequinone derivatives, malono derivatives, and C−H activated carbonyl compounds in the presence of a catalytic amount of 1,4-Diazabicyclo[2.2]octane (DABCO) in ethanol or H2O/EtOH mixture under reflux conditions.
Journal ArticleDOI

Reaction of nitrile ylides with isatins and o-benzoquinones: formation of novel spirooxazoline derivatives

TL;DR: In this article, the base catalysed reaction of imidoyl chlorides underwent dipolar cycloaddition with isatins, phenanthrenequinone and acenaphthenequinone to afford novel spirooxazoline derivatives.
Journal ArticleDOI

An efficient synthesis of versatile synthon 3-chlorooxindoles with NaCl/oxone

TL;DR: In this paper, the authors describe an expedient approach for the direct conversion of indole-3-carboxaldehyde to 3-chlorooxindoles using a simple sustainable synthetic method.
Journal ArticleDOI

One-Pot Access to a Library of Dispiro Oxindole-pyrrolidine/pyrrolothiazole-thiochromane Hybrids via Three-Component 1,3-Dipolar Cycloaddition Reactions.

TL;DR: This experimentally simple protocol provides good yields of structurally complex, biologically relevant heterocycles in a single operation by the three-component 1,3-dipolar cycloaddition of azomethine ylides generated in situ from the condensation of isatins and secondary amino acids.
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