Journal ArticleDOI
Horsfiline, an oxindole alkaloid from Horsfieldia superba
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This article is published in Journal of Organic Chemistry.The article was published on 1991-11-01. It has received 351 citations till now. The article focuses on the topics: Horsfiline & Horsfieldia superba.read more
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Addition of TMSCN to chiral ketimines derived from isatin. Synthesis of an oxindole-based peptidomimetic and a bioactive spirohydantoin.
Alessandro Sacchetti,Alessandra Silvani,Francesco G. Gatti,Giordano Lesma,Tullio Pilati,Beatrice Trucchi +5 more
TL;DR: The Strecker-type reaction of isatin derived chiral ketimines with TMSCN in the presence of a Lewis acid has been investigated and the desired α-amino nitriles have been obtained in good yields with moderate diastereoselectivity.
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A direct synthesis of 2-arylpropenoic acid esters having nitro groups in the aromatic ring: a short synthesis of (±)-coerulescine and (±)-horsfiline †
TL;DR: In this article, a short synthesis of 2-arylpropenoic acid esters that possess nitro groups in their phenyl ring using common and less expensive reagents is described.
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Solid phase approaches to N-heterocycles using a sulfur linker cleaved by SmI2
TL;DR: Two solid-phase approaches to oxindoles and tetrahydroquinolones using a sulfur HASC linker illustrate the compatibility of the linker system with a number of reaction types and its utility for library synthesis.
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Synthesis of gem‐Difluorinated Spiro‐γ‐lactam Oxindoles by Visible‐Light‐Induced Consecutive Difluoromethylative Dearomatization, Hydroxylation, and Oxidation
TL;DR: Several of the functionalized spirooxindole products showed good fungicidal activity, suggesting that they have potential agrochemical applications, and the protocol features high chemo- and regioselectivity, good functional group tolerance, and easy scalability.
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A simple entry to novel spiro dihydroquinoline-oxindoles using Povarov reaction between 3-N-aryliminoisatins and isoeugenol
TL;DR: An easy, fast, and cheap way for the synthesis of the new 4′-(4-hydroxy-3-methoxyphenyl)-3′-methyl-3′,4′-dihydro-1′ H -spiro[indoline-3,2′-quinolin]-2-ones using BF 3 OEt 2 -promoted imino Diels-Alder cycloaddition between ketimine-isatin derivatives and trans- isoeugenol as discussed by the authors.