Journal ArticleDOI
Horsfiline, an oxindole alkaloid from Horsfieldia superba
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This article is published in Journal of Organic Chemistry.The article was published on 1991-11-01. It has received 351 citations till now. The article focuses on the topics: Horsfiline & Horsfieldia superba.read more
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Spirooxindole derivatives that act as analgesics
TL;DR: In this article, the structure of the spirooxindole derivatives has been described, and the present invention relates to certain spirooxide derivatives and to pharmaceutically acceptable salts thereof, which exhibit good analgesic properties and are effective in the treatment of chronic pain.
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Efficient synthesis of spirooxindolyl oxazol-2(5H)-ones via palladium(ii)-catalyzed addition of arylboronic acids to nitriles
TL;DR: In this paper, a versatile synthesis of spirooxindolyl oxazol-2(5H)-ones via palladium(II)-catalyzed addition of arylboronic acids to nitriles is described.
Journal ArticleDOI
Synthesis of Privileged Scaffolds by Using Diversity‐Oriented Synthesis
Ramu Surakanti,Sumalatha Sanivarapu,Chiranjeevi Thulluri,Pravin Iyer,Raghuram S. Tangirala,Rambabu Gundla,Uma Addepally,Y. L. N. Murthy,Lakshmi Velide,Subhabrata Sen +9 more
TL;DR: An elegant reagent-controlled strategy has been developed for the generation of a diverse range of biologically active scaffolds from a chiral bicyclic lactam, and this method directly generated anticancer compounds with potency at low nanomolar concentrations.
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Chemical composition of three Malaysian Horsfieldia essential oils.
Wan Mohd Nuzul Hakimi Wan Salleh,Natasa Mohd Shakri,Shamsul Khamis,William N. Setzer,Muhammad Helmi Nadri +4 more
TL;DR: This study aims to assess the chemical compositions of the essential oils from three Horsfieldia species namely H. fulva Warb, H. sucosa Warb.
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Synthesis of highly functionalized 2-thiaspiro[4.5]deca-6,8-dienes via atom efficient tandem Michael addition/Thorpe–Ziegler cyclization
Mani Anusha Rani,Sundaravel Vivek Kumar,Somi Santharam Roja,Abdulrahman I. Almansour,Raju Suresh Kumar,Shunmuganarayanan Athimoolam,Raju Ranjith Kumar +6 more
TL;DR: The two-component reaction of 2,4-bis((Z)-arylidene)dihydrothiophen-3(2H)-ones and 2-(1-arylethylidenes)malononitriles proceeded through a tandem chemoselective Michael addition–tautomerization–Thorpe–Ziegler cyclization sequence of reactions in a single step affording novel 2-thiaspiro in quantitative yields.