Journal ArticleDOI
Horsfiline, an oxindole alkaloid from Horsfieldia superba
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This article is published in Journal of Organic Chemistry.The article was published on 1991-11-01. It has received 351 citations till now. The article focuses on the topics: Horsfiline & Horsfieldia superba.read more
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Organocatalytic double arylation of 3-isothiocyanato oxindoles: Stereocontrolled synthesis of complex spirooxindoles
Lin-Lin Zhang,Lin-Lin Zhang,Bing-Chao Da,Shao-Hua Xiang,Shuai Zhu,Zi-Yun Yuan,Zhen Guo,Bin Tan +7 more
TL;DR: In this paper, a variety of novel spirooxindoles, possessing a spirocyclic stereocenter adjacent to the aromatic ring, via asymmetric double arylation were synthesized.
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Oxindole synthesis via polar–radical crossover of ketene-derived amide enolates in a formal [3 + 2] cycloaddition
Niklas Radhoff,Armido Studer +1 more
TL;DR: A simple, efficient and transition-metal free method for the preparation of valuable and sterically hindered 3,3-disubstituted oxindoles via polar–radical crossover of ketene derived amide enolates is introduced.
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Three component synthesis of 2-oxindole via sequential Michael addition, intramolecular cyclization and aromatization
TL;DR: An easy metal free access to the synthesis of medicinally promising 2-oxindole derivatives via a tandem enamine formation – Michael addition – regiospecific intramolecular cyclization – aromatization sequence promoted by trifluoroacetic acid has been described.
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Recyclable fluorous cinchona organocatalysts for asymmetric synthesis of biologically interesting compounds
Xin Huang,Wei Zhang +1 more
TL;DR: In this paper, the recyclable cinchona alkaloid-catalyzed reactions including fluorination and Michael addition-initiated cascade reactions in asymmetric synthesis of functionalized compounds of biological interest are presented.
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Simple and efficient routes to substituted oxazolidine and spiro-oxindole systems by one-pot synthetic strategies
Biswajit Gayen,Avijit Banerji +1 more
TL;DR: In either route 1,3-dipolar cycloadditions involving non-stabilised azomethine ylides as intermediates, generated in situ from amino acids and aldehydes, with the dipolarophile present in the reaction mixture viz. (E)-β-nitrostyrene, were utilised.