Journal ArticleDOI
Horsfiline, an oxindole alkaloid from Horsfieldia superba
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This article is published in Journal of Organic Chemistry.The article was published on 1991-11-01. It has received 351 citations till now. The article focuses on the topics: Horsfiline & Horsfieldia superba.read more
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Synthesis of 4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid ethyl ester and its isomer 1-oxo-2,9-dihydro-1H-β-carboline-4-carboxylic acid ethyl ester
Jan Bergman,Stanley Rehn +1 more
TL;DR: An alternative synthesis to this p... was proposed by as discussed by the authors, where they used 3-methylene-oxindole acetic acid ethyl ester to obtain a 4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid ester.
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Catalytic Enantioselective Synthesis of a 3-Aryl-3-benzyloxindole (=3-Aryl-3-benzyl-1,3-dihydro-2H-indol-2-one) Exhibiting Antitumor Activity
Dmitry Katayev,E. Peter Kündig +1 more
TL;DR: A palladium-catalyzed intramolecular α-arylation of an amide in the presence of a bulky chiral N-heterocyclic carbene ligand is the key step in the first catalytic synthesis of (3R)-6-chloro-3-(3-chlorobenzyl)-1,3-dihydro-3,methoxyphenyl)-2H-indol-2-one ((R)-5) as mentioned in this paper.
Journal ArticleDOI
Synthesis of benzoxepinopyrrolidines/spiropyrrolidines via oxa-Pictet–Spengler and [3+2] cycloaddition reactions
TL;DR: In this article, a one-pot synthesis of 2-benzoxepines with paraformaldehyde via oxa-Pictet-Spengler cyclization is described.
Regioselective synthesis, stereochemical structure, spectroscopic characterization and geometry optimization of dispiro(3H-indole-3,
ElSayed M. Shalaby,Adel S. Girgis,A. M. Moustafa,Aida M. ElShaabiny,Bahaa El-Dien,Mohamed Elgendy,Ahmed F. Mabied +6 more
TL;DR: In this article, two dispiro[3H-indole-3,2′-pyrrolidine-3′,3″-piperidines], C31H29Cl2N3O3 (4a) and C32H31Cl2n3O2 (4b), have been synthesized and characterized by IR, 1H NMR, 13C NMR and 1H 1H COSY.
Journal ArticleDOI
Horsfiequinones A-F, dimeric diarylpropanoids from Horsfieldia tetratepala.
TL;DR: Cytotoxicity evaluation against five human tumor lines showed selective inhibitory effects on HL-60 for several compounds tested with IC50 values ranging from 3.18 ±0.67 to 6.61 ± 0.08 µM.