Journal ArticleDOI
Horsfiline, an oxindole alkaloid from Horsfieldia superba
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This article is published in Journal of Organic Chemistry.The article was published on 1991-11-01. It has received 351 citations till now. The article focuses on the topics: Horsfiline & Horsfieldia superba.read more
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Synthesis of first ever 4-quinolone-3-carboxylic acid-appended spirooxindole-pyrrolidine derivatives and their biological applications
Thangaraj Arasakumar,Thangaraj Arasakumar,Sadasivam Mathusalini,Athar Ata,Ramasamy Shankar,Subashini Gopalan,Krishnasamy Lakshmi,Pandiyarajan Sakthivel,Palathurai Subramaniam Mohan +8 more
TL;DR: In vitro cytotoxicity of spirooxindole derivatives (8a–r) was evaluated against MCF-7 breast cancer cell line and DFT studies support the proposed mechanism for this cycloaddition reaction.
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Ynesulfonamide-Based Silica Gel and Alumina-Mediated Diastereoselective Cascade Cyclizations to Spiro[indoline-3,3′-pyrrolidin]-2-ones under Neat Conditions
Yanshi Wang,Xiaoyu Wang,Jingsheng Lin,Bo Yao,Guanghui Wang,Yuandong Zhao,Xinhang Zhang,Bin Lin,Yang Liu,Maosheng Cheng,Yongxiang Liu +10 more
TL;DR: In this paper, the spiro[indoline-3,3′-pyrrolidin]-2-ones were synthesized via a silica gel and alumina-mediated sequential transformation based on tryptamine-derived ynesulfonamide substrates under neat conditions.
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Cu(II)-β-cyclodextrin-catalyzed synthesis of spiro[indoline-3,4′-pyrano[3,2-c]chromene]-3′-carbonitrile derivatives
Seyed Esmail Sadat-Ebrahimi,Seyed Mohammad Haghayegh-Zavareh,Saeed Bahadorikhalili,Azadeh Yahya-Meymandi,Mohammad Mahdavi,Mina Saeedi +5 more
TL;DR: In this paper, the synthesis of spiro[indoline-3,4′-pyrano[3,2-c]chromene]-3′-carbonitriles through the reaction of isatin derivatives, 4-hydroxycoumarin, and malononitrile in ethanol was described.
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Novel cytotoxic acylphenol dimers of Myristica gigantea; enzymatic synthesis of giganteones A and B
TL;DR: In this article, three new compounds, prepromalabaricone B and two dimeric acylphenols, giganteones A (2 ) and B (3 ) were isolated from EtOAc extract of the fruits of Myristica gigantea (Myristicaceae), together with known promalabarsicones C ( 4 ), malabaricones A-C ( 5−7 ) and maingayone ( 8 ).
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One-pot four component domino strategy for the synthesis of novel spirooxindole pyrrolizine linked 1,2,3-triazoles via stereo- and regioselective [3 + 2] cycloaddition reaction in acidic medium
TL;DR: The structures of the compounds synthesized herein were confirmed by 1H N MR, 13C NMR, mass spectra and X-ray crystallographic techniques.