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Horsfiline, an oxindole alkaloid from Horsfieldia superba

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This article is published in Journal of Organic Chemistry.The article was published on 1991-11-01. It has received 351 citations till now. The article focuses on the topics: Horsfiline & Horsfieldia superba.

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Diastereodivergent synthesis of dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties

TL;DR: The different sequence of the cycloaddition and rearrangement stages allows us to perform the targeted synthesis of two diastereomerically pure products from the same starting compounds.
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Synthesis and chemical properties of new derivatives of 3a',6a'-dihydro-2'H-spiro- [indole-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(1H,3'H,5'H)-trione

TL;DR: A series of new 3a',6a'-dihydro-2'H-spiro[indole-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'(1H,3'H,5'H)- triones has been synthesized by cycloaddition of azomethine ylides, obtained from isatins and acyclic aliphatic and sulfur-containing α-amino acids, to maleimides.
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An environmentally benign approach for the synthesis of 3,3′-pyrrolidonyl spirooxindole derivatives via a cascade Knoevenagel–Michael–cyclization multicomponent reaction

TL;DR: In this article, a series of 3,3′-pyrrolidonyl spirooxindole derivatives have been synthesized in good yields from the cascade Knoevenagel-Michael cyclization multicomponent reaction of isatin, malononitrile and α-isothiocyanato imide in the presence of a catalytic amount of triethylamine "on water" assisted with ultrasonic irradiation.
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Palladium-Catalyzed Bis-Functionalization of Isatylidenes: A Facile Route towards Spiro-Indol-2-ones

TL;DR: In this article, an effective protocol was developed for the construction of 3,3-disubstituted indol-2-ones from isatylidenes by utilizing amphiphilic bis-π-allylpalladium and related intermediates.
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Effective and diastereoselective preparation of dispiro[cyclopent-3′-ene]bisoxindoles via novel [3 + 2] annulation of isoindigos and MBH carbonates

TL;DR: A novel and diastereoselective annulation of isoindigos and Morita-Baylis-Hillman carbonates has been developed for the highly efficient and one-step preparation of highly steric dispiro[cyclopent-3'-ene]bisoxindoles with two all-carbon quaternary spirocenters and three adjacent cycles in excellent yields.
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