Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries
Kelechi E Nnoaham,Lone Hummelshoj,Premila Webster,Thomas D'Hooghe,Fiorenzo De Cicco Nardone,Carlo de Cicco Nardone,Crispin Jenkinson,Stephen Kennedy,Krina T. Zondervan,Krina T. Zondervan +9 more
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TLDR
Endometriosis impairs HRQoL and work productivity across countries and ethnicities, yet women continue to experience diagnostic delays in primary care, and a higher index of suspicion is needed to expedite specialist assessment of symptomatic women.About:
This article is published in Fertility and Sterility.The article was published on 2011-08-01 and is currently open access. It has received 1007 citations till now. The article focuses on the topics: Endometriosis & Pelvic pain.read more
Citations
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GnRH and GnRH receptors in the pathophysiology of the human female reproductive system
Roberto Maggi,Anna Cariboni,Marina Montagnani Marelli,Roberta M. Moretti,Valentina Andre,Monica Marzagalli,Patrizia Limonta +6 more
TL;DR: Increasing knowledge about the regulation of GnRH pulsatile release, as well as the therapeutic use of its analogues, offers interesting new perspectives in the diagnosis, treatment and outcome of female reproductive disorders, including tumoral and iatrogenic diseases.
Journal ArticleDOI
Assessing Research Gaps and Unmet Needs in Endometriosis
Sawsan As-Sanie,Rebecca S. Black,Linda C. Giudice,Tanika Gray Valbrun,Jhumka Gupta,Brittany Jones,Marc R. Laufer,Alexandra T. Milspaw,Stacey A. Missmer,Abby Norman,Robert N. Taylor,Kedra Wallace,Zev Williams,Paul J. Yong,Rebecca A. Nebel +14 more
TL;DR: Comprehensive and interdisciplinary approaches to disease management and increased education and disease awareness for patients, health care providers, and the public are needed to remove stigma, increase timely and accurate diagnosis and treatment, and allow for new advancements.
Journal ArticleDOI
Evaluation of a panel of 28 biomarkers for the non-invasive diagnosis of endometriosis
Alexandra Vodolazkaia,Y. El-Aalamat,Dusan Popovic,Attila Mihalyi,Xavier Bossuyt,Cleophas M. Kyama,Cleophas M. Kyama,Amelie Fassbender,Attila Bokor,Attila Bokor,Dominique Schols,Dana Huskens,Christel Meuleman,Karen Peeraer,Carla Tomassetti,Olivier Gevaert,Etienne Waelkens,A. Kasran,B. De Moor,Thomas D'Hooghe +19 more
TL;DR: In plasma samples obtained during menstruation, multivariate analysis of four biomarkers enabled the diagnosis of endometriosis undetectable by US with a sensitivity of 81-90% and a specificity of 63-81% in independent training- and test data set.
Journal ArticleDOI
Genome-Wide DNA Methylation Analysis Predicts an Epigenetic Switch for GATA Factor Expression in Endometriosis
Matthew T. Dyson,Damian Roqueiro,Diana Monsivais,C. Mutlu Ercan,Mary Ellen Pavone,David C. Brooks,Toshiyuki Kakinuma,Masanori Ono,Nadereh Jafari,Yang Dai,Serdar E. Bulun +10 more
TL;DR: The unique epigenetic fingerprint in endometriosis suggests DNA methylation is an integral component of the disease, and identifies a novel role for the GATA family as key regulators of uterine physiology–aberrantDNA methylation in endometricriotic cells correlates with a shift in GATA isoform expression that facilitates progesterone resistance and disease progression.
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Defining Future Directions for Endometriosis Research: Workshop Report From the 2011 World Congress of Endometriosis in Montpellier, France
Peter Rogers,Thomas D'Hooghe,Asgerally T. Fazleabas,Linda C. Giudice,Grant W. Montgomery,Felice Petraglia,Robert N. Taylor +6 more
TL;DR: A consensus workshop to define future directions for endometriosis research was held as part of the 11th World Congress on EndometRIosis in September 2011 in Montpellier, France, and produced this consensus international research priorities statement.
References
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Revised American Fertility Society classification of endometriosis: 1985
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ESHRE guideline for the diagnosis and treatment of endometriosis
Stephen Kennedy,Agneta Bergqvist,Charles Chapron,Thomas D'Hooghe,Gerard A.J. Dunselman,Robert R. Greb,Lone Hummelshoj,Andrew M. Prentice,Ertan Saridogan +8 more
TL;DR: A working group was convened comprised of practising gynaecologists and experts in evidence-based medicine from Europe, as well as an endometriosis self-help group representative, and the guideline was developed and refined.
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