In- and out-of-hospital mortality for myocardial infarction during the first wave of the COVID-19 pandemic in Emilia-Romagna, Italy: A population-based observational study.
Gianluca Campo,Daniela Fortuna,Elena Berti,Rossana De Palma,Giuseppe Di Pasquale,Marcello Galvani,Alessandro Navazio,Giancarlo Piovaccari,Rubboli A,Gabriele Guardigli,Nazzareno Galiè,Giuseppe Boriani,Stefano Tondi,Diego Ardissino,Massimo Piepoli,Federico Banchelli,Andrea Santarelli,Gianni Casella,AMI-Co investigators +18 more
- Vol. 3, pp 100055
TLDR
In Emilia-Romagna, MI hospitalizations significantly decreased during the first wave of the COVID-19 pandemic, except for those with SARS-CoV-2 infection, and a concomitant increase in the out-of-hospital cardiac mortality was observed.Abstract:
Background The COVID-19 pandemic has put several healthcare systems under severe pressure. The present analysis investigates how the first wave of the COVID-19 pandemic affected the myocardial infarction (MI) network of Emilia-Romagna (Italy). Methods Based on Emilia-Romagna mortality registry and administrative data from all the hospitals from January 2017 to June 2020, we analysed: i) temporal trend in MI hospital admissions; ii) characteristics, management, and 30-day mortality of MI patients; iii) out-of-hospital mortality for cardiac cause. Findings Admissions for MI declined on February 22, 2020 (IRR -19.5%, 95%CI from -8.4% to -29.3%, p = 0.001), and further on March 5, 2020 (IRR -21.6%, 95%CI from -9.0% to -32.5%, p = 0.001). The return to pre-COVID-19 MI-related admission levels was observed from May 13, 2020 (IRR 34.3%, 95%CI 20.0%-50.2%, p<0.001). As compared to those before the pandemic, MI patients admitted during and after the first wave were younger and with fewer risk factors. The 30-day mortality remained in line with that expected based on previous years (ratio observed/expected was 0.96, 95%CI 0.84-1.08). MI patients positive for SARS-CoV-2 were few (1.5%) but showed poor prognosis (around 5-fold increase in 30-day mortality). In 2020, the number of out-of-hospital cardiac deaths was significantly higher (ratio observed/expected 1.17, 95%CI 1.08-1.27). The peak was reached in April. Interpretation In Emilia-Romagna, MI hospitalizations significantly decreased during the first wave of the COVID-19 pandemic. Management and outcomes of hospitalized MI patients remained unchanged, except for those with SARS-CoV-2 infection. A concomitant increase in the out-of-hospital cardiac mortality was observed. Funding None.read more
Citations
More filters
COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England
Marion Mafham,Enti Spata,Enti Spata,Raphael Goldacre,Dominic Gair,Paula Curnow,Mark Bray,Sam Hollings,Chris Roebuck,Chris Gale,Mamas A. Mamas,John E. Deanfield,Mark A de Belder,Thomas F Luescher,Tom Denwood,Martin J Landray,Martin J Landray,Jonathan Emberson,Jonathan Emberson,Rory Collins,Eva Morris,Barbara Casadei,Colin Baigent,Colin Baigent +23 more
TL;DR: The reduced number of admissions during this period is likely to have resulted in increases in out-of-hospital deaths and long-term complications of myocardial infarction and missed opportunities to offer secondary prevention treatment for patients with coronary heart disease.
Journal ArticleDOI
Impact of COVID-19 pandemic restrictions on ST-elevation myocardial infarction: a cardiac magnetic resonance imaging study.
Ivan Lechner,Martin Reindl,Christina Tiller,Magdalena Holzknecht,F Troger,Priscilla Fink,Agnes Mayr,Gert Klug,Axel Bauer,Bernhard Metzler,Sebastian J. Reinstadler +10 more
TL;DR: In this article, the impact of the coronavirus disease 2019 (COVID-19) pandemic and associated public health restrictions on infarct severity was explored by cardiac magnetic resonance imaging.
Journal ArticleDOI
Indirect impact of Covid-19 on hospital care pathways in Italy.
Teresa Spadea,Chiara Di Girolamo,Tania Landriscina,Olivia Leoni,Silvia Forni,Paola Colais,Caterina Fanizza,Alessandra Allotta,Roberta Onorati,Roberto Gnavi +9 more
TL;DR: In this paper, the authors retrospectively analyzed hospital discharges data, computing twelve indicators of volume and performance in three clinical areas: cardiology, oncology, and orthopaedics.
Journal ArticleDOI
Effects of non-pharmaceutical interventions against COVID-19 on the incidence of other diseases
Journal ArticleDOI
Variations of the quality of care during the COVID-19 pandemic affected the mortality rate of non-COVID-19 patients with hip fracture
TL;DR: In this paper , the authors measured process and outcome indicators related to the quality of care provided to non-COVID-19 elderly patients affected by hip fractures in Emilia-Romagna, a region of Italy severely hit by the pandemic.
References
More filters
Journal ArticleDOI
Reduced Rate of Hospital Admissions for ACS during Covid-19 Outbreak in Northern Italy.
Ovidio De Filippo,Fabrizio D'Ascenzo,Filippo Angelini,Pier Paolo Bocchino,Federico Conrotto,Andrea Saglietto,Gioel Gabrio Secco,Gianluca Campo,Guglielmo Gallone,Roberto Verardi,Luca Gaido,Mario Iannaccone,Marcello Galvani,Fabrizio Ugo,Umberto Barbero,Vincenzo Infantino,Luca Olivotti,Marco G. Mennuni,Sebastiano Gili,Fabio Infusino,Matteo Vercellino,Ottavio Zucchetti,Gianni Casella,Massimo Giammaria,Giacomo Boccuzzi,Paolo Tolomeo,Baldassarre Doronzo,Gaetano Senatore,Walter Grosso Marra,Andrea Rognoni,Daniela Trabattoni,Luca Franchin,Andrea Borin,Francesco Bruno,Alessandro Galluzzo,Alfonso Gambino,Annamaria Nicolino,Alessandra Truffa Giachet,Gennaro Sardella,Francesco Fedele,Silvia Monticone,Antonio Montefusco,Pierluigi Omedè,Mauro Pennone,Giuseppe Patti,Massimo Mancone,Gaetano M. De Ferrari +46 more
TL;DR: During the Covid-19 outbreak in northern Italy, the daily rate of admissions for acute coronary syndrome at 15 hospitals was significantly lower than in previous outbreaks.
Journal ArticleDOI
Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era.
Salvatore De Rosa,Carmen Spaccarotella,Cristina Basso,Maria Pia Calabrò,Antonio Curcio,Pasquale Perrone Filardi,Massimo Mancone,Giuseppe Mercuro,Saverio Muscoli,Savina Nodari,Roberto Pedrinelli,Gianfranco Sinagra,Ciro Indolfi +12 more
TL;DR: Admissions for AMI were significantly reduced during the COVID-19 pandemic across Italy, with a parallel increase in fatality and complication rates.
Journal ArticleDOI
Out-of-Hospital Cardiac Arrest during the Covid-19 Outbreak in Italy.
Enrico Baldi,Giuseppe Maria Sechi,Claudio Mare,Fabrizio Canevari,Antonella Brancaglione,Roberto Primi,Catherine Klersy,Alessandra Palo,Enrico Contri,Vincenza Ronchi,Giorgio Beretta,Francesca Reali,Pierpaolo Parogni,Fabio Facchin,Davide Bua,Ugo Rizzi,Daniele Bussi,Simone Ruggeri,Luigi Oltrona Visconti,Simone Savastano +19 more
TL;DR: Out- of-Hospital Cardiac Arrest and Covid-19 From February 21 through April 1, 2019, a total of 229 cases of out-of-hospital cardiac arrest were reported in four provinces of Lombardy, Italy.
Journal ArticleDOI
COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England.
Marion Mafham,Enti Spata,Enti Spata,Raphael Goldacre,Dominic Gair,Paula Curnow,Mark Bray,Sam Hollings,Chris Roebuck,Chris Gale,Mamas A. Mamas,John E. Deanfield,Mark A de Belder,Thomas F Luescher,Tom Denwood,Martin J Landray,Martin J Landray,Jonathan Emberson,Jonathan Emberson,Rory Collins,Eva Morris,Barbara Casadei,Colin Baigent,Colin Baigent +23 more
TL;DR: In this article, the authors investigated the effect of the COVID-19 pandemic on admissions of patients with acute coronary syndromes in England and evaluated whether in-hospital management of patients has been affected.
Journal ArticleDOI
Out-of-hospital cardiac arrest during the COVID-19 pandemic in Paris, France: a population-based, observational study.
Eloi Marijon,Nicole Karam,Daniel Jost,David Perrot,Benoit Frattini,Clément Derkenne,Ardalan Sharifzadehgan,Victor Waldmann,Frankie Beganton,Kumar Narayanan,Antoine Lafont,Wulfran Bougouin,Xavier Jouven +12 more
TL;DR: The incidence and outcomes of out-of-hospital cardiac arrest (OHCA) in an urban region during the pandemic, compared with non-pandemic periods was evaluated in adult inhabitants of the study area.
Related Papers (5)
Decreased Mortality Over Time During the First Wave in Patients With COVID-19 in Geriatric Care: Data From the Stockholm GeroCovid Study.
Hong Xu,Sara Garcia-Ptacek,Martin Annetorp,Tommy Cederholm,Georg Engel,Malin Engström,Håkan Erlandsson,Charlotte Julius,Miia Kivipelto,Miia Kivipelto,Lars Göran Lundberg,Carina Metzner,Carina Metzner,Linda Sandberg,Josefina Skogö Nyvang,Carina Sühl Öberg,Elisabet Åkesson,Dorota Religa,Dorota Religa,Maria Eriksdotter,Maria Eriksdotter +20 more