Reduced Rate of Hospital Admissions for ACS during Covid-19 Outbreak in Northern Italy.
Ovidio De Filippo,Fabrizio D'Ascenzo,Filippo Angelini,Pier Paolo Bocchino,Federico Conrotto,Andrea Saglietto,Gioel Gabrio Secco,Gianluca Campo,Guglielmo Gallone,Roberto Verardi,Luca Gaido,Mario Iannaccone,Marcello Galvani,Fabrizio Ugo,Umberto Barbero,Vincenzo Infantino,Luca Olivotti,Marco G. Mennuni,Sebastiano Gili,Fabio Infusino,Matteo Vercellino,Ottavio Zucchetti,Gianni Casella,Massimo Giammaria,Giacomo Boccuzzi,Paolo Tolomeo,Baldassarre Doronzo,Gaetano Senatore,Walter Grosso Marra,Andrea Rognoni,Daniela Trabattoni,Luca Franchin,Andrea Borin,Francesco Bruno,Alessandro Galluzzo,Alfonso Gambino,Annamaria Nicolino,Alessandra Truffa Giachet,Gennaro Sardella,Francesco Fedele,Silvia Monticone,Antonio Montefusco,Pierluigi Omedè,Mauro Pennone,Giuseppe Patti,Massimo Mancone,Gaetano M. De Ferrari +46 more
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During the Covid-19 outbreak in northern Italy, the daily rate of admissions for acute coronary syndrome at 15 hospitals was significantly lower than in previous outbreaks.Abstract:
Acute Coronary Syndrome during Covid-19 Outbreak During the Covid-19 outbreak in northern Italy, the daily rate of admissions for acute coronary syndrome at 15 hospitals was significantly lower tha...read more
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COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives.
TL;DR: The interaction between the viral spike protein and angiotensin-converting enzyme 2, which triggers entry of the virus into host cells, is likely to be involved in the cardiovascular manifestations of COVID-19.
Journal ArticleDOI
COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England.
Marion Mafham,Enti Spata,Enti Spata,Raphael Goldacre,Dominic Gair,Paula Curnow,Mark Bray,Sam Hollings,Chris Roebuck,Chris Gale,Mamas A. Mamas,John E. Deanfield,Mark A de Belder,Thomas F Luescher,Tom Denwood,Martin J Landray,Martin J Landray,Jonathan Emberson,Jonathan Emberson,Rory Collins,Eva Morris,Barbara Casadei,Colin Baigent,Colin Baigent +23 more
TL;DR: In this article, the authors investigated the effect of the COVID-19 pandemic on admissions of patients with acute coronary syndromes in England and evaluated whether in-hospital management of patients has been affected.
Journal ArticleDOI
Hypertension, thrombosis, kidney failure, and diabetes: Is covid-19 an endothelial disease? a comprehensive evaluation of clinical and basic evidence
Celestino Sardu,Celestino Sardu,Jessica Gambardella,Marco Bruno Morelli,Xujun Wang,Raffaele Marfella,Gaetano Santulli +6 more
TL;DR: A systematic and comprehensive evaluation of both clinical and preclinical evidence supporting the hypothesis that the endothelium is a key target organ in COVID-19 is reported, providing a mechanistic rationale behind its systemic manifestations.
Journal ArticleDOI
Trends in Emergency Department Visits and Hospital Admissions in Health Care Systems in 5 States in the First Months of the COVID-19 Pandemic in the US.
Molly M. Jeffery,Gail D'Onofrio,Hyung Paek,Timothy F. Platts-Mills,William E. Soares,Jason A. Hoppe,Nicholas Genes,Bidisha Nath,Edward R. Melnick +8 more
TL;DR: This cross-sectional study examines trends in emergency department visits and visits that led to hospitalizations during a 4-month period leading up to and during the COVID-19 outbreak in the US.
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Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort.
Janice L. Atkins,Jane A. H. Masoli,Jane A. H. Masoli,João Delgado,Luke C. Pilling,Luke C. Pilling,Chia-Ling Kuo,George A. Kuchel,David Melzer,David Melzer +9 more
TL;DR: There are specific high-risk preexisting comorbidities for CO VID-19 hospitalization and related deaths in community-based older men and women and these results do not support simple age-based targeting of the older population to prevent severe COVID-19 infections.
References
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A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
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Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response.
TL;DR: An emergency task force was formed by the Government of Lombardy and local health authorities to lead the response to the outbreak and a forecast of estimated ICU demand over the coming weeks is provided.
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