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Interactions in multispecies biofilms: do they actually matter?

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TLDR
The recent focus on complex bacterial communities has led to the recognition of interactions across species boundaries, particularly pronounced in multispecies biofilms, where synergistic interactions impact the bacterial distribution and overall biomass produced.
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This article is published in Trends in Microbiology.The article was published on 2014-02-01. It has received 400 citations till now.

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Metagenomic characterization of bacterial biofilm in four food processing plants in Colombia.

TL;DR: The results indicate that different bacterial genera of interest to the food industry due to their ability to form biofilm and affect food quality can coexist inside biofilms, and as such, persist in production environments, representing a constant risk for manufactured foods.
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It is all about location: how to pinpoint microorganisms and their functions in multispecies biofilms.

TL;DR: The pros and cons of fluorescence-based techniques used to decipher bacterial species patterns in biofilms at single cell level are discussed, including fluorescence in situ hybridization and the use of genetically modified bacteria that express fluorescent proteins, reporting the significant improvements of those techniques.
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Activity of Biodegradable Polymeric Nanosponges against Dual-Species Bacterial Biofilms

TL;DR: The described engineered nanosponges demonstrated broad-spectrum antimicrobial activity through prevention of dual-species biofilm formation as well as eradication of preformed biofilms and showed no toxicity against mammalian cells, highlighting the therapeutic potential of this platform.
References
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Journal ArticleDOI

Bacterial biofilms : A common cause of persistent infections

TL;DR: Improvements in understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections.
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The biofilm matrix

TL;DR: The functions, properties and constituents of the EPS matrix that make biofilms the most successful forms of life on earth are described.
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Bacterial biofilms: from the natural environment to infectious diseases.

TL;DR: It is evident that biofilm formation is an ancient and integral component of the prokaryotic life cycle, and is a key factor for survival in diverse environments.
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Mechanisms of biofilm resistance to antimicrobial agents

TL;DR: Owing to the heterogeneous nature of the biofilm, it is likely that there are multiple resistance mechanisms at work within a single community.
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Survival strategies of infectious biofilms.

TL;DR: Current concepts of biofilm tolerance are reviewed with special emphasis on the role of the biofilm matrix and the physiology ofBiofilm-embedded cells, and the heterogeneity in metabolic and reproductive activity within a biofilm correlates with a non-uniform susceptibility of enclosed bacteria.
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