Journal ArticleDOI
Keratin-hydrotalcites hybrid films for drug delivery applications
Tamara Posati,Demetra Giuri,Morena Nocchetti,Anna Sagnella,Marzia B. Gariboldi,Claudia Ferroni,Giovanna Sotgiu,Greta Varchi,Roberto Zamboni,Annalisa Aluigi +9 more
TLDR
In this article, a novel hybrid materials for drug delivery purposes are obtained by combining keratin with hydrotalcite nanoparticles containing diclofenac, and the hybrid films showed a less pronounced swelling, porosity and degradation and a greater thermal stability compared to pure keratin films containing free DICLOFenac.About:
This article is published in European Polymer Journal.The article was published on 2018-08-01. It has received 47 citations till now. The article focuses on the topics: Drug delivery & Hydrotalcite.read more
Citations
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Journal ArticleDOI
Biofunctionalization of Natural Fiber-Reinforced Biocomposites for Biomedical Applications.
TL;DR: This paper offers a detailed overview of the extraction and separation processes applied to natural fibers and their posterior chemical and physical modifications for biocomposite fabrication.
Journal ArticleDOI
Overview of Protein-Based Biopolymers for Biomedical Application
Sakthivel Nagarajan,Socrates Radhakrishnan,S. Narayana Kalkura,Sebastien Balme,Philippe Miele,Philippe Miele,Mikhael Bechelany +6 more
TL;DR: Protein based biopolymers derived from animals and plants, one of the promising class of biomaterials due to their biocompatibility and biodegradability, are discussed.
Journal ArticleDOI
DOX-Conjugated keratin nanoparticles for pH-Sensitive drug delivery
TL;DR: The drug release results showed that KDNPs performed an excellent pH-sensitive behavior under acidic tumor microenvironment and exhibited the enhanced cytotoxicity against A549 cells, and higher therapeutic efficiency in vivo than free DOX.
Journal ArticleDOI
Nano-hybrid electrospun non-woven mats made of wool keratin and hydrotalcites as potential bio-active wound dressings
Demetra Giuri,Marianna Barbalinardo,Giovanna Sotgiu,Roberto Zamboni,Morena Nocchetti,Anna Donnadio,Franco Corticelli,Francesco Valle,Chiara G.M. Gennari,Francesca Selmin,Tamara Posati,Annalisa Aluigi +11 more
TL;DR: The cell viability test indicated a decreased toxicity of the drug when loaded into nanofibers and confirmed the biocompatibility of keratin/HTD electrospun non-woven mats; moreover, a controlled diclofenac release within the first 24 hours does not compromise the fibroblast cell growth in a significant manner.
Journal ArticleDOI
From fabric to tissue: Recovered wool keratin/polyvinylpyrrolidone biocomposite fibers as artificial scaffold platform.
Giulia Suarato,Marco Contardi,Giovanni Perotto,José A. Heredia-Guerrero,Fabrizio Fiorentini,Luca Ceseracciu,Cataldo Pignatelli,Doriana Debellis,Rosalia Bertorelli,Athanassia Athanassiou +9 more
TL;DR: This study presents, for the first time, keratin-PVP biocomposite fibers obtained via an all-water co-electrospinning process and explored their properties modulation as a result of different thermal crosslinking treatments.
References
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Journal ArticleDOI
A Review of Keratin-Based Biomaterials for Biomedical Applications
Jillian G. Rouse,Mark Van Dyke +1 more
TL;DR: The history of keratin research and the advancement of Keratin biomaterials for biomedical applications are discussed.
Journal ArticleDOI
Fourier Transform Infrared and Raman Spectroscopic Study of the Local Structure of Mg-, Ni-, and Co-Hydrotalcites
J. Theo Kloprogge,Ray L. Frost +1 more
TL;DR: In this article, the FT-IR and FT-Raman spectroscopy were used to characterize synthetic Mg-, Ni- and Co-hydrotalcite, and they showed that the composition changes brought about by changing the divalent metal result in small but significant changes in band positions of the modes related to the hydroxyl groups.
Journal ArticleDOI
Biodegradable Materials Based on Silk Fibroin and Keratin
TL;DR: The nonlinear trend of the different parameters obtained from FTIR analysis and DSC curves of both SF/keratin systems indicate that when proteins are mixed they do not follow additives rules but are able to establish intermolecular interactions.
Journal ArticleDOI
Fabrication of wool keratin sponge scaffolds for long-term cell cultivation.
TL;DR: Results show that wool keratin sponges are useful scaffolds for long-term and high-density cell cultivation and have a homogeneously porous microstructure.
Journal ArticleDOI
Layered nanomaterials for green materials
TL;DR: In this paper, the applications of layered nanomaterials as green materials are demonstrated along with their structures and properties, and various eco-friendly materials can be hybridized with layered nanoparticles such as layered double hydroxides (LDHs), hydroxy double salts (HDSs) and cationic clays.
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A Review of Keratin-Based Biomaterials for Biomedical Applications
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