Journal ArticleDOI
Kinetics of Dimethylamine Nitrosation in Relation to Nitrosamine Carcinogenesis
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This article is published in Journal of the National Cancer Institute.The article was published on 1970-03-01. It has received 145 citations till now. The article focuses on the topics: Dimethylamine & Nitrosation.read more
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N-nitrosamine formation from atrazine.
TL;DR: More persistent pesticides or their degradative products capable of forming N-nitroso derivatives should be investigated and pathways of degradation, both chemical and biological, should be elucidated.
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Rapid formation of carcinogenic N-nitrosamines by interaction of nitrite with fungicides derived from dithiocarbamic acid in vitro under simulated gastric conditions and in vivo in the rat stomach
TL;DR: In vitro formation of the carcinogen dimethylnitrosamine (DMN) from the fungicide bis(dimethyldithiocarbamato)zinc (ziram) in the presence of sodium nitrite has been studied in vitro under conditions similar to those existing in the stomach and also in vivo in the rat.
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Decomposition of N-nitrosamines, and concomitant release of nitric oxide by Fenton reagent under physiological conditions.
TL;DR: Electron spin resonance (ESR) studies indicate that the N-nitrosamines were decomposed accompanying concomitant release of NO on contact with reactive oxygen species.
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Fourier Transform infrared analysis below the one-nanogram level
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Theoretical investigation of N-nitrosodimethylamine formation from dimethylamine nitrosation catalyzed by carbonyl compounds.
TL;DR: Fluoral is proposed as a good catalyst for the nitrosation of DMA by nitrite anion, which has a calculated energy barrier of about 26 kcal/mol, and will help elucidate the mechanisms of formation of nitrosamines.