Journal ArticleDOI
Kinetics of Dimethylamine Nitrosation in Relation to Nitrosamine Carcinogenesis
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This article is published in Journal of the National Cancer Institute.The article was published on 1970-03-01. It has received 145 citations till now. The article focuses on the topics: Dimethylamine & Nitrosation.read more
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Urinary Dimethylamine (DMA) and Its Precursor Asymmetric Dimethylarginine (ADMA) in Clinical Medicine, in the Context of Nitric Oxide (NO) and Beyond.
TL;DR: In healthy subjects and in rheumatoid arthritis patients, the urinary excretion rate of DMA correlates positively with the excreted rate of dihydroxyphenylglycol (DHPG), the major urinary catecholamines metabolite, suggesting a potential interplay in the PRMT/DDAH/NO pathway.
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Recent synthetic applications of n-nitrosamines and related compounds
TL;DR: In this paper, the authors present a list of recent applications of N-NITROSAMINES and RELATED COMPOUNDS in the field of organic preparation and procedures.
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Comparative toxicology of N-nitroso compounds and their carcinogenic potential to man.
E.J. Olajos,Frederick Coulston +1 more
TL;DR: In vitro and in vivo formation, chemistry, and bioconversion of N -nitroso compounds are discussed, along with recent developments pertaining to nitrosamine-induced transplacental carcinogenesis.
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Kinetics of the nitrosation of aminopyrine to give dimethylnitrosamine
TL;DR: The initial rate of nitrosation of aminopyrine to give dimethyl nitrosamine (DMN) showed maxima at pH 2.0 and 3.1, indicating that nitrous anhydride formation was rate-limiting at pH 1 and rate was proportional to nitrite concentration squared down to 6 mM, below which it decreased rapidly.