Journal ArticleDOI
Large diameter primary afferent input is required for expression of the Cat-301 proteoglycan on the surface of motor neurons.
Robert G. Kalb,Susan Hockfield +1 more
TLDR
It is reported that the expression of the Cat-301 proteoglycan on motor neurons depends on primary afferent input in the early postnatal period, and input relayed by large diameterPrimary afferents is required for normal maturation of motor neuronal properties during early life.About:
This article is published in Neuroscience.The article was published on 1990-01-01. It has received 61 citations till now. The article focuses on the topics: Motor neuron & Premovement neuronal activity.read more
Citations
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Journal ArticleDOI
Synaptic Control of Motoneuronal Excitability
TL;DR: A background description of motoneurons: their development, anatomical organization, and membrane properties, both passive and active, and a description of the major transmitter systems that affect mot oneuronal excitability, focusing on synaptic and cellular properties.
Journal ArticleDOI
The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system.
TL;DR: The development of methods to remove CSPGs has considerable therapeutic potential in a number of CNS disorders and may be involved in the pathological processes in diseases such as epilepsy, stroke and Alzheimer's disease.
Journal ArticleDOI
Extracellular matrix of the central nervous system: from neglect to challenge.
TL;DR: The basic concept, that specialized extracellular matrices rich in hyaluronan, chondroitin sulfate proteoglycans, link proteins and tenascins can regulate cellular migration and axonal growth and thus, actively participate in the development and maturation of the nervous system, has in recent years gained rapidly expanding experimental support.
Journal ArticleDOI
Perineuronal nets — a specialized form of extracellular matrix in the adult nervous system
Marco R. Celio,Ingmar Blümcke +1 more
TL;DR: In the adult brain the molecules constituting the 'perineuronal nets of matrix' could serve as recognition molecules between certain neurons and their surrounding cells and participate in the selection and consolidation of their relationship.
Journal ArticleDOI
Perineuronal nets provide a polyanionic, glia-associated form of microenvironment around certain neurons in many parts of the rat brain.
Gert Brückner,Kurt Brauer,Wolfgang Härtig,Joachim R. Wolff,Michael Rickmann,Amin Derouiche,Bertrand Delpech,Nicole Girard,Wolfgang H. Oertel,Andreas Reichenbach +9 more
TL;DR: It is concluded that perineuronal nets are composed of a specialized type of glia‐associated extracellular matrix rich in polyanionic groups and N‐acetylgalactosamine, similar to the ensheathment of nodes of Ranvier.
References
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Handbook of Physiology.
TL;DR: This is the first volume of the proposed many-sectioned "Handbook" in which the American Physiological Society intends to present comprehensively the entire field of physiology.
Journal ArticleDOI
Segregation of form, color, movement, and depth: anatomy, physiology, and perception
TL;DR: Perceptual experiments can be designed to ask which subdivisions of the system are responsible for particular visual abilities, such as figure/ground discrimination or perception of depth from perspective or relative movement--functions that might be difficult to deduce from single-cell response properties.
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The period of susceptibility to the physiological effects of unilateral eye closure in kittens
David H. Hubel,Torsten N. Wiesel +1 more
TL;DR: Kittens were visually deprived by suturing the lids of the right eye for various periods of time at different ages to study the effect of monocular eye closure on the number of cells that can be influenced by the previously closed eye.
Book
The Nervous System
TL;DR: The Nervous System as discussed by the authors is a series of intriguing essays ranging over terror, state fetishism, shamanic healing in Latin America, homesickness, and the place of the tactile eye in both magic and modernity.