Leukocyte-endothelial adhesion molecules.
Timothy M. Carlos,John M. Harlan +1 more
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TLDR
Investigations have progressed from the early descriptions by intravital microscopy and histology, to functional and immunologic characterization of adhesion molecules, and now to the development of genetically deficient animals and the first phase I trial of "anti-adhesion" therapy in humans.About:
This article is published in Blood.The article was published on 1994-10-01 and is currently open access. It has received 2732 citations till now. The article focuses on the topics: Cell adhesion & Cell adhesion molecule.read more
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Lymphocyte homing and homeostasis.
TL;DR: A review of the molecular basis of lymphocyte homing is presented, and mechanisms by which homing physiology regulates the homeostasis of immunologic resources are proposed.
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Endothelial Progenitor Cells: Characterization and Role in Vascular Biology
Carmen Urbich,Stefanie Dimmeler +1 more
TL;DR: This review summarizes the mechanisms regulating endothelial progenitor cell–mediated neovascularization and reendothelialization and describes the characterization of the different progenitors cell populations.
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Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers.
Tucker Collins,Margaret Read,Andrew S. Neish,Maryann Z. Whitley,Dimitris Thanos,Tom Maniatis +5 more
TL;DR: A model has been proposed for the cytokine‐induced E‐selectin enhancer that is similar to the stereospecific complex proposed forThe inter‐ feron‐β gene promoter, in which multiple DNA bending proteins facilitate the assembly of higher order complexes of transcriptional activators that interact as a unit with the basal transcriptional machinery.
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Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration
TL;DR: Recent findings show that the "traffic signals" for lymphocyte recirculation and for neutrophil and monocyte localization in inflammation are strikingly similar at the molecular level.
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T-cell function and migration. Two sides of the same coin.
TL;DR: This review will concentrate on the migration of T cells, which are at the heart of most adaptive immune responses, since T cells respond to pathogens only on direct contact with pathogen-derived antigen.