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Journal ArticleDOI

Long-Term Follow-Up of 1,000 Patients Cured of Helicobacter pylori Infection Following an Episode of Peptic Ulcer Bleeding

TLDR
Peptic ulcer rebleeding virtually does not occur in patients with complicated ulcers after H. pylori eradication, and maintenance anti-ulcer (antisecretory) therapy is not necessary if eradication is achieved.
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This article is published in The American Journal of Gastroenterology.The article was published on 2012-08-01. It has received 72 citations till now. The article focuses on the topics: Helicobacter pylori.

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Citations
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Journal ArticleDOI

Fifth Chinese National Consensus Report on the management of Helicobacter pylori infection.

TL;DR: Since the ‘Fourth Chinese National Consensus Report on the management of H. pylori infection’ was published in 2012, three important consensuses (Kyoto global consensus report on H.pylori gastritis, The Toronto Consensus for the Treatment ofH. pylonori infection and the Maastricht V/Florence Consensus report) have been published regarding the management.
Journal ArticleDOI

Helicobacter pylori associated chronic gastritis, clinical syndromes, precancerous lesions, and pathogenesis of gastric cancer development

TL;DR: Patients with precancerous lesions (molecular alterations) that do not reverse after H. pylori treatment, represent the "point of no return" and may be at high risk for the development of GC, therefore, earlier H.pylori eradication should be considered for preventing GC development prior to the appearance of precancersous lesions.
References
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Journal ArticleDOI

Helicobacter pylori in Peptic Ulcer Disease

TL;DR: It is concluded that ulcer patients with H. pylori infection require treatment with antimicrobial agents in addition to antisecretory drugs whether on first presentation with the illness or on recurrence.
Journal ArticleDOI

Bleeding peptic ulcer.

TL;DR: Although hospitalization and surgery for uncomplicated ulcers have decreased in the United States and Europe over the past 20 to 30 years, the number of hospital admissions for hemorrhage associated with ulcers has remained relatively unchanged.
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Preventing Recurrent Upper Gastrointestinal Bleeding in Patients With Helicobacter Pylori Infection Who Are Taking Low-Dose Aspirin or Naproxen

TL;DR: Among patients with H. pylori infection and a history of upper gastrointestinal bleeding who are taking low-dose aspirin, the eradication of H.pylori is equivalent to treatment with omeprazole in preventing recurrent bleeding.
Journal ArticleDOI

Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use

TL;DR: In patients who had ulcer complications related to the long-term use of low-dose aspirin, treatment with lansoprazole in addition to the eradication of H. pylori infection significantly reduced the rate of recurrence of ulcers complications.
Journal ArticleDOI

Relationship between Helicobacter pylori eradication and reduced duodenal and gastric ulcer recurrence: a review

TL;DR: The current literature strongly suggests that H. pylori eradication 4 weeks after therapy should be used as the primary efficacy end point for reduced gastric and duodenal ulcer recurrence for the purpose of clinical trial design.
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