Mangiferin: a natural miracle bioactive compound against lifestyle related disorders
Muhammad Imran,Muhammad Imran,Muhammad Sajid Arshad,Muhammad Sajid Arshad,Masood Sadiq Butt,Joong-Ho Kwon,Muhammad Umair Arshad,Muhammad Tauseef Sultan +7 more
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The current review article is an attempt to explain the therapeutic potential of mangiferin, a bioactive compound of the mango, against lifestyle-related disorders and its associated health claims.Abstract:
The current review article is an attempt to explain the therapeutic potential of mangiferin, a bioactive compound of the mango, against lifestyle-related disorders. Mangiferin (2-β-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one) can be isolated from higher plants as well as the mango fruit and their byproducts (i.e. peel, seed, and kernel). It possesses several health endorsing properties such as antioxidant, antimicrobial, antidiabetic, antiallergic, anticancer, hypocholesterolemic, and immunomodulatory. It suppresses the activation of peroxisome proliferator activated receptor isoforms by changing the transcription process. Mangiferin protects against different human cancers, including lung, colon, breast, and neuronal cancers, through the suppression of tumor necrosis factor α expression, inducible nitric oxide synthase potential, and proliferation and induction of apoptosis. It also protects against neural and breast cancers by suppressing the expression of matrix metalloproteinase (MMP)-9 and MMP-7 and inhibiting enzymatic activity, metastatic potential, and activation of the β-catenin pathway. It has the capacity to block lipid peroxidation, in order to provide a shielding effect against physiological threats. Additionally, mangiferin enhances the capacity of the monocyte-macrophage system and possesses antibacterial activity against gram-positive and gram-negative bacteria. This review summarizes the literature pertaining to mangiferin and its associated health claims.read more
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Heavy metal associated health hazards: An interplay of oxidative stress and signal transduction.
Jagdish Gopal Paithankar,Sanjay Saini,Shiwangi Dwivedi,Anurag Sharma,Debapratim Kar Chowdhuri +4 more
TL;DR: An effort has been made to decipher the interplay among heavy metals/metalloids exposures, oxidative stress, and signal transduction, which are essential to mount the cellular and organismal response.
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Chemical Composition of Mango (Mangifera indica L.) Fruit: Nutritional and Phytochemical Compounds.
María Elena Maldonado-Celis,Elhadi M. Yahia,Ramiro Bedoya,Patricia Landázuri,Nelsy Loango,Johanny Aguillón,Beatriz Restrepo,Juan Camilo Guerrero Ospina +7 more
TL;DR: In this article, a comprehensive update on the composition of mango fruit, including nutritional and phytochemical compounds, and the changes of these during development and postharvest is presented.
Chemical composition of mango (mangifera indica l.) fruit : Nutritional and phytochemical compound
María Elena Maldonado Celis,Elhadi Yahia Kazuz,Ramiro Bedoya,Patricia Landázuri,Nelsy Loango Chamorro,Johanny Aguillón Osma,Beatriz Restrepo,Juan Camilo Guerrero Ospina +7 more
TL;DR: The present manuscript is a comprehensive update on the composition of mango fruit, including nutritional and phytochemical compounds, and the changes of these during development and postharvest.
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Effect of feed supplementation with biosynthesized silver nanoparticles using leaf extract of Morus indica L. V1 on Bombyx mori L. (Lepidoptera: Bombycidae).
Sudip Some,Onur Bulut,Onur Bulut,Kinkar Biswas,Anoop Kumar,Anupam Roy,Ipsita K. Sen,Amitava Mandal,Octavio L. Franco,Octavio L. Franco,İkbal Agah İnce,Kartik Neog,Sandip Das,Sayantan Pradhan,Subhadeep Dutta,Debjoy Bhattacharjya,Soumen Saha,Pradeep K. Das Mohapatra,Anil Bhuimali,B. G. Unni,Ahmet Kati,Amit Kumar Mandal,M. Deniz Yilmaz,Ismail Ocsoy +23 more
TL;DR: The synthesis of silver nanoparticles (AgNPs) by a green route using the aqueous leaf extract of Morus indica L. V1 showed beneficial effects on the survivability, body weights of the Bombyx mori L. larvae, pupae, cocoons and shells weights via enhancing the feed efficacy.
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Nutritional Composition and Bioactive Compounds in Three Different Parts of Mango Fruit
TL;DR: In this article, the authors provide nutraceutical and pharmacological information on all three parts of mango to understand the defense mechanisms of its functional constituents, and the appropriate use of mangoes to enhance our nutrition and health.
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Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats
TL;DR: It is demonstrated that mangiferin possesses significant antidiabetic, antihyperlipidemic and antiatherogenic properties thus suggesting its beneficial effect in the treatment of diabetes mellitus associated with hyperlipidemia and related cardiovascular complications.
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