Journal ArticleDOI
Metabolic profiling for studying chemotype variations in Withania somnifera (L.) Dunal fruits using GC-MS and NMR spectroscopy.
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TLDR
The variation in the metabolite concentration among different chemotypes of the fruits of W. somnifera suggest that specific chemovars can be used to obtain substantial amounts of bioactive ingredients for use as potential pharmacological and nutraceuticals agents.About:
This article is published in Phytochemistry.The article was published on 2013-09-01. It has received 60 citations till now. The article focuses on the topics: Withania somnifera & Chemotype.read more
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Nutritional and medicinal applications of Moringa oleifera Lam.—Review of current status and future possibilities
TL;DR: In this article, the role of biotechnology in conservation and genetic enhancement of nutritional, medicinal and commercial value of the tree has been placed in perspective, together with an up-date review on phytochemical analysis of the plant, and its utility has been discussed to invite the attention of the scientific community to further consider the study of this miracle tree species and its nutritional and pharmaceutical properties.
Journal ArticleDOI
Current Insights into the Biological Action of Squalene
José M. Lou-Bonafonte,José M. Lou-Bonafonte,Roberto Martínez-Beamonte,Roberto Martínez-Beamonte,Teresa Sanclemente,Joaquín C. Surra,Joaquín C. Surra,Luis V. Herrera-Marcos,Javier Sánchez-Marco,Carmen Arnal,Carmen Arnal,Jesús Osada,Jesús Osada +12 more
TL;DR: A systematic review of studies concerning squalene published in the last 8 years has provided further support for its antioxidant, anti-inflammatory, and anti-atherosclerotic properties in vivo and in vitro.
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Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological aspects.
Subhabrata Paul,Shreya Chakraborty,Uttpal Anand,Swarnali Dey,Samapika Nandy,Mimosa Ghorai,Suchismita Chatterjee Saha,Manoj Patil,Ramesh Kandimalla,Jarosław Proćków,Abhijit Dey +10 more
TL;DR: In this article, a comprehensive summary of the geographical distribution, traditional use, phytochemistry, and pharmacological activities of W. somnifera and its active constituents are presented.
Journal ArticleDOI
Enhanced Cellular Internalization: A Bactericidal Mechanism More Relative to Biogenic Nanoparticles than Chemical Counterparts.
Madhuree Kumari,Shatrunajay Shukla,Shipra Pandey,Ved Prakash Giri,Anil Bhatia,Tusha Tripathi,Poonam Kakkar,Chandra Shekhar Nautiyal,Aradhana Mishra +8 more
TL;DR: Study reveals that biologically synthesized silver nanoarchitecture coated with antimicrobial metabolites of T. viride was more potent than their chemical counterpart in killing of pathogenic bacteria.
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Metabolic profiling of Commiphora wightii (guggul) reveals a potential source for pharmaceuticals and nutraceuticals.
Anil Bhatia,Santosh Kumar Bharti,Tusha Tripathi,Anuradha Mishra,O. P. Sidhu,Raja Roy,Chandra Shekhar Nautiyal +6 more
TL;DR: Very high concentrations of quinic acid and myo-inositol in leaves and fruits; a substantial quantity of α-tocopherol and NMP in leaves, trans-farnesol in fruits, bostrycin and deoxybostryzin from its endophyte makes the taxa distinct, since these metabolites with medicinal properties find immense applications as dietary supplements and nutraceuticals.
References
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Journal ArticleDOI
Metabolite profiling for plant functional genomics.
Oliver Fiehn,Joachim Kopka,Peter Dörmann,Thomas Altmann,Richard N. Trethewey,Lothar Willmitzer +5 more
TL;DR: The use of metabolite profiling is described as a new tool for a comparative display of gene function and has the potential not only to provide deeper insight into complex regulatory processes but also to determine phenotype directly.
Journal Article
Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.
TL;DR: Preliminary studies have found various constituents of ashwagandha exhibit a variety of therapeutic effects with little or no associated toxicity, indicating this herb should be studied more extensively to confirm these results and reveal other potential therapeutic effects.
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Metabolic redesign of vitamin E biosynthesis in plants for tocotrienol production and increased antioxidant content.
Edgar B. Cahoon,Sarah E. Hall,Kevin G. Ripp,Thaya S Ganzke,William D. Hitz,Sean J. Coughlan,Sean J. Coughlan,Sean J. Coughlan +7 more
TL;DR: Insight is provided into the genetic basis for tocotrienol biosynthesis in plants and the ability to enhance the antioxidant content of crops by introduction of an enzyme that redirects metabolic flux is demonstrated.
Journal ArticleDOI
Chemopreventive effect of squalene on colon cancer.
TL;DR: The finding that Squalene significantly suppresses colonic ACF formation and crypt multiplicity strengthens the hypothesis that squalene possesses chemopreventive activity against colon carcinogenesis.
Journal ArticleDOI
Tocochromanol functions in plants: antioxidation and beyond
Jon Falk,Sergi Munné-Bosch +1 more
TL;DR: The antioxidant function of tocochromanols in plants is reviewed, with particular attention to specific roles attributed to different tocopherol homologues (particularly alpha- and gamma-tocopherol) and the possible functions of tocotrienols, which are only present in a range of unrelated plant groups and are almost exclusively found in seeds and fruits.