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Journal ArticleDOI

Micro-PIV investigation of the internal flow transitions inside droplets traveling in a rectangular microchannel

TLDR
In this paper, the internal flow field of droplets traveling in a rectangular microchannel by means of microparticle image velocimetry is studied. And the effects of capillary number, viscosity ratio and interfacial tension on the flow topology are investigated.
Abstract
This paper discusses the studies on the internal flow field of droplets traveling in a rectangular microchannel by means of microparticle image velocimetry, specifically concentrating on the effects of capillary number, viscosity ratio and interfacial tension. The flow topology is predominantly dependent on the capillary number. It shows that the evident transitions from three pairs of recirculation zones at lower capillary numbers to one pair of recirculation zones near the sidewalls with low velocity in the central area at intermediate capillary numbers, then to a pair of recirculation zones closest to the axial centerline with high velocity in the central area at higher capillary numbers. There are two critical capillary numbers increasing with viscosity ratio in the evolution of flow features. Droplet size only influences two velocity components values other than the flow topology within intervals separated by the critical values. The equilibrium mechanism of viscous friction force and Marangoni stress dominate the internal topological transition in a surfactant added system. The obtained internal fluid phenomena inside droplets are beneficial to provide a guideline for screening of biochemical reaction conditions in the device.

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Citations
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Journal ArticleDOI

Two-phase flow and mass transfer in microchannels: A review from local mechanism to global models

TL;DR: In this article, the authors present a review of the recent progress on flow and mass transfer of two-phase systems in microchannels, in a multi-scale view from local mechanism to global behavior.
Journal ArticleDOI

New insights into the pressure during the merged droplet formation in the squeezing time

TL;DR: In this paper, a three-dimensional numerical simulation of the merged droplet formation (MDF) in the double T-junction microchannel was performed to investigate the effects of the flow rate of the continuous phase, continuous viscosity and the interfacial tension on the pressure by the level-set method.
Journal ArticleDOI

Velocity distributions in trapped and mobilized non-wetting phase ganglia in porous media

TL;DR: Micro-particle tracking velocimetry in a micro-fluidic model is used in order to visualise the velocity distributions inside the trapped phase globules prior and during mobilisation, and time-averaged and instantaneous velocity vectors have been determined using fluorescent microscopy.
Journal ArticleDOI

Breakup dynamics of droplets in an asymmetric bifurcation by μPIV and theoretical investigations

TL;DR: In this article, the mass conservation law was used to predict the geometric shape of droplets in an asymmetric bifurcation and the critical neck thickness that determines whether a droplet will break after flowing through the split.
Journal ArticleDOI

Internal flow patterns of a droplet pinned to the hydrophobic surfaces of a confined microchannel using micro-PIV and VOF simulations

TL;DR: In this paper, both experimental results and numerical simulations of a droplet pinned to the hydrophobic surfaces of a confined microfluidic channel, as a result of contact angle hysteresis, are presented.
References
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Journal ArticleDOI

Single-cell analysis and sorting using droplet-based microfluidics

TL;DR: A droplet-based microfluidics protocol for high-throughput analysis and sorting of single cells, and a binding assay for detecting antibodies secreted from single mouse hybridoma cells is detailed.
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Droplet based microfluidics

TL;DR: This paper will review available drop generation and manipulation techniques in droplet based microfluidics to identify and shed light on similarities and underlying physical principles.
Journal ArticleDOI

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TL;DR: This critical review discusses the current understanding of the formation, transport, and merging of drops in microfluidics and focuses on the physical ingredients which determine the flow of Drops in microchannels.
Journal ArticleDOI

The pressure drop along rectangular microchannels containing bubbles.

TL;DR: A systematic and quantitative investigation of the influence of surfactants on the flow of fluids in microchannels containing bubbles using an indirect method to derive the pressure in the channel.
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