Microplastics: A Threat for Male Fertility
TLDR
In this paper, the main changes in sperm quality along the lifespan and the upcoming studies on the effects of microplastics in male fertility in mammals are summarized and discussed. But the effect of MP exposure on male reproduction and sperm quality is poorly known.Abstract:
Much of the planet is swimming in discarded plastic, which is harming animal and possibly human health. Once at sea, sunlight, wind, and wave action break down plastic waste into small particles: the microplastics (MPs). Currently, particular attention has been drawn to their effects on aquatic environments but the health risks, especially in mammals, are poorly known. These non-biodegradable materials can act as a vector for environmental pollutants, can be ingested by humans in food and water, and can enter and accumulate in human tissues with a possible risk for heath. Recent studies revealed the deleterious effects of MPs exposure in male reproduction and sperm quality, making them a potential hazard to reproductive success. This manuscript summarizes the main changes in sperm quality along the lifespan and the upcoming studies on the effects of MPs in male fertility in mammals.read more
Citations
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Journal ArticleDOI
Micro(nano)plastics pollution and human health: A carcinogenesis concern for humans.
Rakesh Kumar,Camelia Manna,Shaveta Padha,Anurag Verma,P. Sharma,Anjali Dhar,Ashok Ghosh,S. Bhattacharya +7 more
TL;DR: In this article , the authors highlight MPs and NPs pathways to the food chain and how these plastic particles can cause risks to human health, such as respiratory, immune, reproductive, and digestive systems.
Journal ArticleDOI
Comparing the effects of polystyrene microplastics exposure on reproduction and fertility in male and female mice
TL;DR: In this article, male and female C57BL/6 mice were exposed to saline or 0.1 mg/d polystyrene microplastics for 30 days or 44 days to determine the effects of MPs on reproductive systems, following which some of the mice were caged for 10 days to mate to test fertility.
Journal ArticleDOI
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway
Haibo Jin,Minghao Yan,Chun Pan,Zhenyu Liu,Xiaoxuan Sha,Chengyue Jiang,Luxi Li,Mengge Pan,Dongmei Li,Xiaodong Han,Jie Ding +10 more
TL;DR: In this article , the effects of exposure to polystyrene microplastics (MPs) on the male reproductive system of mice were investigated and it was shown that chronic exposure to MPs resulted in toxicity of male reproduction under environmental exposure levels and these potential risks may ring alarm bells of public health.
Journal ArticleDOI
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway
Haibo Jin,Minghao Yan,Chun Pan,Zhenyu Liu,Xiaoxuan Sha,Chengyue Jiang,Luxi Li,Mengge Pan,Dongmei Li,Xiaodong Han,Jie Ding +10 more
TL;DR: In this article , the effects of exposure to polystyrene microplastic microplastics (MPs) on the male reproductive system of mice were investigated. And the results showed that chronic exposure to MPs resulted in toxicity of male reproduction under environmental exposure levels, which may ring alarm bells of public health.
Journal ArticleDOI
Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice.
Chiang-Wen Lee,Lee-Fen Hsu,I-Lin Wu,Yung-Li Wang,Wei-Chen Chen,Yan-jun Liu,Lubin Yang,Chong-Lun Tan,Yueh Hsia Luo,Chia-Ching Wang,H. W. Chiu,Thomas C.-K. Yang,Yen Yue Lin,Hsin-An Chang,Yao-Chang Chiang,Ching Hsiang Chen,Ming-Hsueh Lee,Kuo-Ti Peng,Cathy C.Y. Huang +18 more
TL;DR: In this paper , the adverse impacts of polystyrene MPs on the brain and hippocampal learning and memory were investigated in mice, showing that exposure to MPs in mice alters the expression of neuronal activity-dependent genes and synaptic proteins, and increases neuroinflammation in the hippocampus, subsequently causing behavioral changes through the vagus nerve-dependent pathway.
References
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