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Journal ArticleDOI

miR-543 inhibites cervical cancer growth and metastasis by targeting TRPM7.

Xiao-ying Liu, +2 more
- 01 Apr 2019 - 
- Vol. 302, pp 83-92
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TLDR
It is found that miR-543 was significantly downregulated in 69 CC tissue samples and cell lines when compared to adjacent normal tissues and cell line, which might serve as a potential biomarker for CC diagnosis and therapy.
About: 
This article is published in Chemico-Biological Interactions.The article was published on 2019-04-01. It has received 42 citations till now. The article focuses on the topics: Cell growth & Metastasis.

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Citations
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Journal ArticleDOI

LncRNA PCAT6 Accelerates the Progression and Chemoresistance of Cervical Cancer Through Up-Regulating ZEB1 by Sponging miR-543

Zhongping Ma, +3 more
- 07 Feb 2020 - 
TL;DR: LncRNA PCAT6 facilitated the proliferation, metastasis and chemoresistance of CC cells to cisplatin while impeded the apoptosis ofCC cells via PCAT 6/miR-543/ZEB1 axis, which might be a promising target for CC therapy.
Journal ArticleDOI

THUMPD3-AS1 Is Correlated With Non-Small Cell Lung Cancer And Regulates Self-Renewal Through miR-543 And ONECUT2.

Jia Hu, +6 more
- 19 Nov 2019 - 
TL;DR: It is indicated that THUMPD3-AS1 regulated NSCLC cell self-renewal by regulating the expression of miR-543 and ONECUT2, and THUM PD3- AS1 can potentially act as a biomarker or therapeutic target in NSCLc.
Journal ArticleDOI

miR-543 promoted the cell proliferation and invasion of nasopharyngeal carcinoma by targeting the JAM-A.

Xue Jiang, +2 more
- 19 Aug 2019 - 
TL;DR: Evidence indicated the important roles of miR-543/JAM-A signaling in the progression of NPC, highlighting the potential ofmiR- 543 as a target in the treatment of NPC.
Journal ArticleDOI

LncRNA CRNDE Promotes ATG4B-Mediated Autophagy and Alleviates the Sensitivity of Sorafenib in Hepatocellular Carcinoma Cells.

Lingxi Chen, +16 more
- 01 Jan 2021 - 
TL;DR: In this paper, the authors showed that CRNDE triggered autophagy via upregulating ATG4B in hepatocellular carcinoma (HCC) cells, which attenuates the sensitivity of sorafenib in HCC cells.
Journal ArticleDOI

Long non-coding RNA PVT1-mediated miR-543/SERPINI1 axis plays a key role in the regulatory mechanism of ovarian cancer.

Chong Qu, +4 more
- 26 Jun 2020 - 
TL;DR: PVT1 can mediate the molecular mechanism of OC by miR-543/SERPINI1 axis regulatory network, which is a new therapeutic direction for OC.
References
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Journal ArticleDOI

Global cancer statistics

Ahmedin Jemal, +4 more
- 01 Jan 1999 - 
TL;DR: A substantial proportion of the worldwide burden of cancer could be prevented through the application of existing cancer control knowledge and by implementing programs for tobacco control, vaccination, and early detection and treatment, as well as public health campaigns promoting physical activity and a healthier dietary intake.
Journal ArticleDOI

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008.

Jacques Ferlay, +5 more
- 15 Dec 2010 - 
TL;DR: The results for 20 world regions are presented, summarizing the global patterns for the eight most common cancers, and striking differences in the patterns of cancer from region to region are observed.
Journal ArticleDOI

Human Papillomavirus and Cervical Cancer

Eileen M. Burd
- 01 Jan 2003 - 
TL;DR: Currently, the clearest role for HPV DNA testing is to improve diagnostic accuracy and limit unnecessary colposcopy in patients with borderline or mildly abnormal cytologic test results.
Journal ArticleDOI

MicroRNAs in cancer: biomarkers, functions and therapy.

Josie Hayes, +2 more
- 01 Aug 2014 - 
TL;DR: The potential applications of microRNAs for the clinical assessment of patient outcome in cancer, as well as in cancer monitoring and therapy are reviewed.
Journal ArticleDOI

Circulating microRNAs: New biomarkers in diagnosis, prognosis and treatment of cancer (Review)

Alessandro Allegra, +6 more
- 01 Dec 2012 - 
TL;DR: The role of circulating miRNAs could be particularly relevant in the context of neoplastic diseases, and the profiling of alterations in circulating miRNA that may signal a predisposition to cancer, could also be a therapeutic target in these patients.
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- 01 Sep 2015 - 

MiR-139-3p induces cell apoptosis and inhibits metastasis of cervical cancer by targeting NOB1.

Ping Huang, +2 more
- 01 Oct 2016 - 

miR-99a and -99b inhibit cervical cancer cell proliferation and invasion by targeting mTOR signaling pathway

Li Wang, +7 more
- 26 Mar 2014 - 

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