Journal ArticleDOI
Myricitrin exhibits antioxidant, anti-inflammatory and antifibrotic activity in carbon tetrachloride-intoxicated mice.
Robert Domitrović,Khaled Rashed,Olga Cvijanović,Sanda Vladimir-Knežević,Marko Škoda,Alenka Višnić +5 more
TLDR
Myricitrin provided better hepatoprotection when compared to silymarin, which is consistent with its higher in vitro antioxidant potential.About:
This article is published in Chemico-Biological Interactions.The article was published on 2015-03-25. It has received 146 citations till now. The article focuses on the topics: Myricitrin & Aspartate transaminase.read more
Citations
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Myricitrin Alleviates Oxidative Stress-induced Inflammation and Apoptosis and Protects Mice against Diabetic Cardiomyopathy.
TL;DR: Results strongly indicate that Myr exerts cardioprotective effects against DCM through the blockage of inflammation, oxidative stress, and apoptosis, and suggests that Myr might be a potential therapeutic agent for the treatment of DCM.
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Solid Lipid Nanoparticles of Myricitrin Have Antioxidant and Antidiabetic Effects on Streptozotocin-Nicotinamide-Induced Diabetic Model and Myotube Cell of Male Mouse.
TL;DR: SLN of myricitrin showed antioxidant, antidiabetic, and antiapoptotic effects in the mouse and myotube cells, and improved diabetes and hyperglycemia complications in the in vivo and in vitro studies.
Journal ArticleDOI
Gastrointestinal stability of dihydromyricetin, myricetin, and myricitrin: an in vitro investigation.
TL;DR: It is concluded that the low bioavailability of these flavonoids may be due to their poor stability in the GI tract, and it is the pH, rather than the presence of pepsin or pancreatin, which most strongly influences the stability of these three flavonoid.
Journal ArticleDOI
Ethnobotany, phytochemistry and neuropharmacological effects of Petiveria alliacea L. (Phytolaccaceae): A review
Diandra Araújo Luz,Alana Miranda Pinheiro,Mallone Lopes Silva,Marta Chagas Monteiro,Rui Daniel Prediger,Cristiane Socorro Ferraz Maia,Enéas Andrade Fontes-Júnior +6 more
TL;DR: The available data reviewed here support the emergence of P. alliacea as a potential source for the treatment of different CNS disorders including anxiety, depression, pain, epilepsy and memory impairments, but further studies are certainly required to improve the knowledge about the mechanisms of action, toxicity and efficacy of the plant.
Journal ArticleDOI
Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants.
Farida Larit,Khaled M. Elokely,Narayan D. Chaurasiya,Samira Benyahia,Manal A. Nael,Francisco León,M. S. Abu-Darwish,Thomas Efferth,Yan-Hong Wang,Djamila Belouahem-Abed,Samir Benayache,Babu L. Tekwani,Stephen J. Cutler +12 more
TL;DR: Evaluated compounds of Hypericum afrum and Cytisus villosus have properties indicative of potential neuroprotective ability and may be new candidates for selective MAO-A and B inhibitors and the most important residues involved in the selective recognition of molecules in the MAOs enzymatic clefts are identified.
References
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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
TL;DR: This assay is very reproducible and rapid with the dye binding process virtually complete in approximately 2 min with good color stability for 1 hr with little or no interference from cations such as sodium or potassium nor from carbohydrates such as sucrose.
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Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
TL;DR: Using this method, the liped peroxide level in the liver of rats suffering from carbon tetrachloride intoxication was investigated and was in good agreement with previously reported data obtained by measuring diene content.
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Antioxidant Determinations by the Use of a Stable Free Radical
TL;DR: In this paper, the chemical nature of the antioxidant is known and a test specific for the compound or group of interest; for example, the nitroprusside test for sulphydryl groups.
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Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
TL;DR: The use of the foregoing analytical method in the determination of total and oxidized glutathione contents of rat blood, kidney, and liver gave values in good agreement with those obtained by previous investigators.
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Oxidative Stress, Inflammation, and Cancer: How Are They Linked?
TL;DR: Observations to date suggest that oxidative stress, chronic inflammation, and cancer are closely linked.