Nanoparticles—Attractive Carriers of Antimicrobial Essential Oils
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TLDR
Essential oil-loaded nanoparticles may offer the potential benefits of synergism in antimicrobial activity, high loading capacity, increased solubility, decreased volatility, chemical stability, and enhancement of the bioavailability and shelf life of EOs and their constituents.Abstract:
Microbial pathogens are the most prevalent cause of chronic infections and fatalities around the world. Antimicrobial agents including antibiotics have been frequently utilized in the treatment of infections due to their exceptional outcomes. However, their widespread use has resulted in the emergence of multidrug-resistant strains of bacteria, fungi, viruses, and parasites. Furthermore, due to inherent resistance to antimicrobial drugs and the host defence system, the advent of new infectious diseases, chronic infections, and the occurrence of biofilms pose a tougher challenge to the current treatment line. Essential oils (EOs) and their biologically and structurally diverse constituents provide a distinctive, inexhaustible, and novel source of antibacterial, antiviral, antifungal, and antiparasitic agents. However, due to their volatile nature, chemical susceptibility, and poor solubility, their development as antimicrobials is limited. Nanoparticles composed of biodegradable polymeric and inorganic materials have been studied extensively to overcome these limitations. Nanoparticles are being investigated as nanocarriers for antimicrobial delivery, antimicrobial coatings for food products, implantable devices, and medicinal materials in dressings and packaging materials due to their intrinsic capacity to overcome microbial resistance. Essential oil-loaded nanoparticles may offer the potential benefits of synergism in antimicrobial activity, high loading capacity, increased solubility, decreased volatility, chemical stability, and enhancement of the bioavailability and shelf life of EOs and their constituents. This review focuses on the potentiation of the antimicrobial activity of essential oils and their constituents in nanoparticulate delivery systems for a wide range of applications, such as food preservation, packaging, and alternative treatments for infectious diseases.read more
Citations
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Encapsulation of essential oils and their application in antimicrobial active packaging
Agnes R. Mukurumbira,Robert A. Shellie,Russsell S. J. Keast,Enzo A. Palombo,Snehal R. Jadhav +4 more
TL;DR: A review of currently available encapsulation techniques and their effect on the antimicrobial efficacy, release profiles, stability and sensory properties of the essential oils can be found in this paper , where the application of encapsulated essential oils in biodegradable active packaging is explored.
Journal ArticleDOI
Essential Oils as Antimicrobial Active Substances in Wound Dressings
Daniela Gheorghita,Elena Grosu,Alina Mihaela Robu,Lia-Mara Ditu,Iuliana Mihaela Deleanu,Gratiela Gradisteanu Pircalabioru,Anca Daniela Raiciu,Ana-Iulia Bita,Aurora Antoniac,Vasile Iulian Antoniac +9 more
TL;DR: The results showed that the essential oils used provide an effective solution as active substances in wound dressings.
Journal ArticleDOI
An Up-To-Date Review Regarding Cutaneous Benefits of Origanum vulgare L. Essential Oil
Larisa Bora,Stefana Avram,Ioana Zinuca Pavel,Delia Muntean,Sergio Liga,Valentina Buda,Daniela Gurgus,Corina Danciu +7 more
TL;DR: The review brings to the fore the most recent findings in the dermatological field regarding potential plant-based therapies involving OvEo, emphasizing the modern pharmaceutical formulation approaches and the cutaneous benefits in skin disorders.
Journal ArticleDOI
Application of Nanomaterials in the Prevention, Detection, and Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA)
TL;DR: The current potential of synthetic or biomimetic nanomaterials/vesicles employed in vaccines, rapid diagnostics, antibiotic delivery, and nanotherapeutics are discussed, with a focus on detecting and treating MRSA.
Journal ArticleDOI
Essential Oil-Based Nanoparticles as Antimicrobial Agents in the Food Industry
TL;DR: The use of essential oils (EO) loaded with nanoparticles is the most promising alternative to increase food quality and safety as mentioned in this paper . But such compounds have some physicochemical properties that prevent commercial use.
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