Journal ArticleDOI
New method of derivatization and headspace solid-phase microextraction for gas chromatographic-mass spectrometric analysis of amphetamines in hair.
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TLDR
A simple method for hair analysis of methamphetamine (MAMP) and amphetamine (AMP) by gas chromatography-mass spectrometry (GC-MS) was developed using simultaneous headspace solid-phase microextraction (HS-SPME) with derivatization.About:
This article is published in Journal of Chromatography B: Biomedical Sciences and Applications.The article was published on 2001-07-05. It has received 54 citations till now. The article focuses on the topics: Solid-phase microextraction & Solid phase extraction.read more
Citations
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Journal ArticleDOI
State of the art in hair analysis for detection of drug and alcohol abuse.
Fritz Pragst,Marie Balíková +1 more
TL;DR: Improved chromatographic-mass spectrometric techniques with increased selectivity and sensitivity and new methods of sample preparation have substantially enhanced the ability to detect numerous drugs and other poisons in hair.
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Recent advances in sample preparation techniques for effective bioanalytical methods
TL;DR: This paper reviews the recent developments in bioanalysis sample preparation techniques and gives an update on basic principles, theory, applications and possibilities for automation, and a comparative discussion on the advantages and limitation of each technique.
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New trends in sample preparation for clinical and pharmaceutical analysis
TL;DR: In this paper, a review of sample preparation techniques for forensic, clinical and pharmaceutical analysis, with special focus on in-tube solid-phase microextraction and related new techniques, is presented.
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Derivatization in mass spectrometry--1. Silylation.
TL;DR: Advances in silylation as a powerful tool used for increasing the volatility, thermal and thermo-catalytic stability, and chromatographic mobility of polar and unstable organic compounds are described.
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Recent developments and applications of microextraction techniques in drug analysis
TL;DR: This review focuses primarily on microextraction techniques developed over the last decade, and presents a summary of the characteristics of various approaches in drug analysis.
References
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Journal ArticleDOI
Detection of methamphetamine and amphetamine in a single human hair by gas chromatography/chemical ionization mass spectrometry.
TL;DR: The high sensitivity enabled the method to measure both stimulants in a single human hair in actual cases, and the detection limit was about 10 pg in an injected volume.
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Quantitative and qualitative analysis of MDMA, MDEA, MA and amphetamine in urine by head-space/solid phase micro-extraction (SPME) and GC/MS
TL;DR: In this article, the results of qualitative and quantitative analysis of some amphetamines and their analogs isolated from urine samples by solid phase micro-extraction with polydimethylsiloxane fibers are reported.
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Automated determination of 'Ecstasy' and amphetamines in urine by SPME and capillary gas chromatography after propylchloroformate derivatisation.
TL;DR: The determination of amphetamines and their methylenedioxylated analogs in urine by propylchloroformate derivatisation and automated solid-phase microextraction is described, shown to be highly reproducible and robust with respect to variations in the urine matrices.
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Simple and simultaneous analysis of fenfluramine, amphetamine and methamphetamine in whole blood by gas chromatography-mass spectrometry after headspace-solid phase microextraction and derivatization.
TL;DR: A simple and sensitive method for the simultaneous analysis of fenfluramine, amphetamine and methamphetamine in whole blood was developed using a headspace-solid phase microextraction (SPME) and derivatization and was applied to a suicide case in which the victim ingested fenFLuramine.
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Simple extractive derivatization of methamphetamine and its metabolites in biological materials with Extrelut columns for their GC-MS determination
TL;DR: A simple, extractive heptafluoro-n-butyrylation with Extrelut columns was devised and AMP, MAMP, and HMAMP could be determined in an actual forensic case study.