Journal ArticleDOI
Non-cytotoxic effect of green synthesized silver nanoparticles and its antibacterial activity.
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TLDR
Interestingly, cytotoxicity of the synthesised AgNPs was less toxic to HaCaT cells as compared to bacteria cells, which suggests that the synthesized AgNBP by this method is eco-friendly in nature.Abstract:
Silver nanoparticles (AgNPs) were green synthesized using ethanolic extract of fenugreek leaves and characterized using UV-Vis spectroscopy, Fourier transform infra-red spectroscopy (FTIR), X-ray diffraction (XRD), high resolution transmission electron microscopy HRTEM and energy dispersive X-ray analysis (EDX) techniques. The HRTEM results revealed the formation of highly stable, mono dispersed, spherical shaped AgNPs with the size ranging from 20 to 30nm. The presence of flavonoids and their interaction with the AgNPs were confirmed using FTIR. Antibacterial activities of the AgNPs were studied against pathogenic gram-positive Staphylococcus aureus (S. aureus) and gram negative Escherichia coli (E. coli) bacteria. The synthesized AgNPs displayed the enhancement of antibacterial activity against E. coli. The morphological changes in the bacterial cell membrane was observed using SEM analysis. Leakage of protein from the bacterial cells increased at every time intervals (2 and 4h). MTT assay was carried out for the AgNPs against human skin cell line (HaCaT). Interestingly, cytotoxicity of the synthesized AgNPs was less toxic to HaCaT cells as compared to bacteria cells, which suggests that the synthesized AgNPs by this method is eco-friendly in nature.read more
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Journal ArticleDOI
Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview
Alexandra-Cristina Burdușel,Oana Gherasim,Alexandru Mihai Grumezescu,L Mogoantă,Anton Ficai,Ecaterina Andronescu +5 more
TL;DR: This review focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based Nanostructure.
Journal ArticleDOI
Synthesis and Application of Silver Nanoparticles (Ag NPs) for the Prevention of Infection in Healthcare Workers
Shingo Nakamura,Masahiro Sato,Yoko Sato,Naoko Ando,Tomohiro Takayama,Masanori Fujita,Masayuki Ishihara +6 more
TL;DR: This review outlines the synthesis and utilization of Ag NPs in the medical field, focusing on environment-friendly synthesis and the suppression of infections in healthcare workers (HCWs).
Journal ArticleDOI
Green synthesis of silver nanoparticles via Cynara scolymus leaf extracts: The characterization, anticancer potential with photodynamic therapy in MCF7 cells.
Ömer Erdoğan,Mürüvvet Abbak,Gulen Melike Demirbolat,Fatih Birtekocak,Mehran Aksel,Salih Paşa,Ozge Cevik +6 more
TL;DR: Biosynthesized AgNPs showed a broad-spectrum anti-cancer activity with PDT therapy and therefore represent promoting ROS generation by modulating mitochondrial apoptosis induction in MCF7 breast cancer cells.
Journal ArticleDOI
Applications of Noble Metal-Based Nanoparticles in Medicine
TL;DR: The characteristics of noble metal-based nanoparticles are introduced with particular emphasis on their applications in medicine and related sciences.
Journal ArticleDOI
A colorimetric hydrogen sulfide sensor based on gellan gum-silver nanoparticles bionanocomposite for monitoring of meat spoilage in intelligent packaging
Xiaodong Zhai,Li Zhihua,Jiyong Shi,Huang Xiaowei,Zongbao Sun,Di Zhang,Xiaobo Zou,Yue Sun,Junjun Zhang,Melvin Holmes,Yun Yun Gong,Megan Povey,Shaoyun Wang +12 more
TL;DR: A colorimetric hydrogen sulfide (H2S) sensor based on gellan gum capped silver nanoparticles was developed to real-time monitor meat spoilage for intelligent food packaging and presented visible color changes from yellow to colorless by in situ and nondestructively sensing H2S generated from chicken breast and silver carp in a packaging system.
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