Journal ArticleDOI
Non-molecular detection of carbapenemases in Enterobacteriaceae clinical isolates
TLDR
An overview of the currently available non-molecular methods for detection of carbapenemase activity is provided and none of thecurrently available phenotypic methods have proved to be full specific and sensitive.About:
This article is published in Journal of Infection and Chemotherapy.The article was published on 2017-01-01. It has received 56 citations till now.read more
Citations
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Journal ArticleDOI
NDM Metallo-β-Lactamases and Their Bacterial Producers in Health Care Settings.
TL;DR: New Delhi metallo-β-lactamase will remain a severe challenge in health care settings, and more studies on appropriate countermeasures are required, as commonly used phenotypic tests cannot specifically identify NDM.
Journal ArticleDOI
Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry in Clinical Microbiology: What Are the Current Issues?
TL;DR: The success of MALDI-TOF MS in clinical microbiology is discussed and fields of application that are still amenable to improvement are highlighted to highlight.
Journal ArticleDOI
Multicenter Evaluation of the Xpert Carba-R Assay for Detection of Carbapenemase Genes in Gram-Negative Isolates.
TL;DR: The Cepheid Xpert Carba-R assay, previously demonstrated to be effective for the detection of carbapenemase genes in rectal swabs, is also adequate for the Detection of these genes in bacterial colonies isolated from blood and MacConkey agars.
Journal ArticleDOI
Prospective evaluation of the OKN K-SeT assay, a new multiplex immunochromatographic test for the rapid detection of OXA-48-like, KPC and NDM carbapenemases.
Youri Glupczynski,Agnès B Jousset,Stéphanie Evrard,Rémy A. Bonnin,Te-Din Huang,Laurent Dortet,Pierre Bogaerts,Thierry Naas +7 more
TL;DR: The OKN assay is efficient, rapid and easy to implement in the workflow of a clinical microbiology laboratory for the confirmation of OXA-48, NDM and KPC carbapenemases without the need for more costly and less frequently available molecular assays.
Journal ArticleDOI
Characterization of VIM-1-Producing E. coli Isolated From a German Fattening Pig Farm by an Improved Isolation Procedure.
Alexandra Irrgang,Bernd-Alois Tenhagen,Natalie Pauly,Silvia Schmoger,Annemarie Kaesbohrer,Annemarie Kaesbohrer,Jens A. Hammerl +6 more
TL;DR: It is assumed that the prevalence of CPEs in animal production in Germany and other European countries might be underestimated and there is a concern of further spread of VIM-1-producing bacteria in German livestock and food.
References
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Journal ArticleDOI
Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance
A-P Magiorakos,Arjun Srinivasan,R B Carey,Yehuda Carmeli,Matthew E. Falagas,Matthew E. Falagas,Christian G. Giske,Stéphan Juergen Harbarth,Janet F. Hindler,Gunnar Kahlmeter,Barbro Olsson-Liljequist,David L. Paterson,Louis B. Rice,John Stelling,Marc Struelens,Alkiviadis Vatopoulos,J T Weber,Dominique L Monnet +17 more
TL;DR: A group of international experts came together through a joint initiative by the European Centre for Disease Prevention and Control and the Centers for Disease Control and Prevention, to create a standardized international terminology with which to describe acquired resistance profiles in Staphylococcus aureus, Enterococcus spp.
Journal ArticleDOI
Carbapenemases: the versatile beta-lactamases.
Anne Marie Queenan,Karen Bush +1 more
TL;DR: The characteristics, epidemiology, and detection of the carbapenemases found in pathogenic bacteria are updates and metallo-β-lactamases are detected primarily in Pseudomonas aeruginosa.
Journal ArticleDOI
Global spread of Carbapenemase-producing Enterobacteriaceae.
TL;DR: These resistance traits have been identified among nosocomial and community-acquired infections and are being investigated for use in drug discovery and development.
Journal ArticleDOI
The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria
TL;DR: In this article, the authors reported that the detection of Klebsiella pneumoniae carbapenemases (KPC) producing bacteria may be difficult based on routine antibiotic susceptibility testing.
Journal ArticleDOI
Carbapenem resistance in Enterobacteriaceae: here is the storm!
TL;DR: This review summarizes the current knowledge on carbapenem resistance in Enterobacteriaceae, including activity, distribution, clinical impact, and possible novel antibiotic pathways.
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