Noninvasive Visualization of microRNA by Bioluminescence Imaging
Gang Niu,Xiaoyuan Chen +1 more
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This article is published in Molecular Imaging and Biology.The article was published on 2009-03-01 and is currently open access. It has received 7 citations till now. The article focuses on the topics: Bioluminescence imaging.read more
Citations
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Journal ArticleDOI
Functional nanoparticles for molecular imaging guided gene delivery
TL;DR: In this review, recent developments of nanoparticles for molecular imaging guided gene delivery are summarized.
Journal ArticleDOI
Recent advances in high-performance fluorescent and bioluminescent RNA imaging probes.
TL;DR: This review summarizes the state-of-the-art high-performance RNA imaging probes, including exogenous probes that can image RNA sequences with special modification and endogeneous probes thatCan directly image endogenous RNAs without special treatment.
Journal ArticleDOI
Molecular imaging of microRNAs
TL;DR: The current brief discussion focuses on the reporter and fluorescent beacon imaging approaches to visualize miRNA expression in living subjects.
Book ChapterDOI
Functional Nanoparticles for Molecular Imaging-Guided Gene Delivery and Therapy
TL;DR: In this review, recent developments of nanoparticles for molecular imaging guided gene delivery are summarized.
Journal ArticleDOI
Molecular imaging of cell-based cancer immunotherapy
TL;DR: This review will summarize the application of multiple molecular imaging modalities in cell-based cancer immunotherapy by tracking cells and monitoring the therapeutic effects of transplanted cells in vivo.
References
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Journal ArticleDOI
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
TL;DR: Two small lin-4 transcripts of approximately 22 and 61 nt were identified in C. elegans and found to contain sequences complementary to a repeated sequence element in the 3' untranslated region (UTR) of lin-14 mRNA, suggesting that lin- 4 regulates lin- 14 translation via an antisense RNA-RNA interaction.
Journal Article
Oncomirs : microRNAs with a role in cancer
TL;DR: I MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function as negative gene regulators as discussed by the authors, and have been shown to repress the expression of important cancer-related genes and might prove useful in the diagnosis and treatment of cancer.
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Oncomirs — microRNAs with a role in cancer
TL;DR: Evidence has shown that miRNA mutations or mis-expression correlate with various human cancers and indicates that miRNAs can function as tumour suppressors and oncogenes.
Journal ArticleDOI
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
TL;DR: This Review summarizes the current understanding of the mechanistic aspects of microRNA-induced repression of translation and discusses some of the controversies regarding different modes of micro RNA function.
Journal ArticleDOI
MicroRNA gene expression deregulation in human breast cancer.
Marilena V. Iorio,Manuela Ferracin,Chang Gong Liu,Angelo Veronese,Riccardo Spizzo,Silvia Sabbioni,Eros Magri,Massimo Pedriali,Muller Fabbri,Manuela Campiglio,Sylvie Ménard,Juan P. Palazzo,Anne L. Rosenberg,Piero Musiani,Stefano Volinia,Italo Nenci,George A. Calin,Patrizia Querzoli,Massimo Negrini,Carlo M. Croce +19 more
TL;DR: It is shown that, compared with normal breast tissue, miRNAs are also aberrantly expressed in human breast cancer, and the overall miRNA expression could clearly separate normal versus cancer tissues, with the most significantly deregulated mi RNAs being mir-125b, mir-145, mir -21, and mir-155.