Novel mechanistic insights into treadmill exercise based rescue of social defeat-induced anxiety-like behavior and memory impairment in rats.
Gaurav Patki,Naimesh Solanki,Fatin Atrooz,Amber Ansari,Farida Allam,Brittany Jannise,Jaganmohan Maturi,Samina Salim +7 more
TLDR
The data suggests involvement of epigenetic mechanisms including histone acetylation of H3 and modulation of methyl-CpG-binding in the hippocampus that might contribute to the rescue effects of exercise in SD-induced behavioral deficits in rats.About:
This article is published in Physiology & Behavior.The article was published on 2014-05-10 and is currently open access. It has received 63 citations till now. The article focuses on the topics: Social defeat & Social stress.read more
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Intermittent metabolic switching, neuroplasticity and brain health
TL;DR: How intermittent metabolic switching, repeating cycles of a metabolic challenge that induces ketosis (fasting and/or exercise) followed by a recovery period (eating, resting and sleeping), may optimize brain function and resilience throughout the lifespan is considered, with a focus on the neuronal circuits involved in cognition and mood.
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Defeat stress in rodents: From behavior to molecules.
Caroline Hammels,Ehsan Pishva,Jochen De Vry,Daniel L.A. van den Hove,Jos Prickaerts,Ruud van Winkel,Jean-Paul Selten,Klaus-Peter Lesch,Nikolaos P. Daskalakis,Harry W.M. Steinbusch,Jim van Os,Gunter Kenis,Bart P. F. Rutten +12 more
TL;DR: The general principle of social defeat stress paradigms are explained, with a strong focus on the resident-intruder model, and the molecular adaptations that are found in animals subjected to defeat stress are provided, with special attention to neural circuits and neuroendocrine signaling.
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Physical exercise as an epigenetic modulator of brain plasticity and cognition.
TL;DR: New developments in the epigenetic field connecting exercise with changes in cognitive function, including DNA methylation, histone modifications and microRNAs (miRNAs) are discussed.
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Neuropeptide Regulation of Signaling and Behavior in the BNST
Thomas L. Kash,Kristen E. Pleil,Catherine A. Marcinkiewcz,Emily G. Lowery-Gionta,Nicole A. Crowley,Christopher M. Mazzone,Jonathan A. Sugam,J. Andrew Hardaway,Zoe A. McElligott +8 more
TL;DR: The goal of this review is to explore the role of peptide signaling in one specific structure, the bed nucleus of the stria terminalis, that has proven to be a fertile ground for peptide action.
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Grape powder prevents cognitive, behavioral, and biochemical impairments in a rat model of posttraumatic stress disorder.
TL;DR: Protective role of GP is suggested in SPS-induced behavioral, cognitive, and biochemical impairments in rats, perhaps, epigenetic regulation of brain-derived neurotrophic factor enables GP-mediated prevention of S PS-induced deficits in rats.
References
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The Rat Brain in Stereotaxic Coordinates
George Paxinos,Charles Watson +1 more
TL;DR: This paper presents a meta-analyses of the determinants of earthquake-triggered landsliding in the Czech Republic over a period of 18 months in order to establish a probabilistic framework for estimating the intensity of the earthquake.
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Sheldon Cohen,Thomas Ashby Wills +1 more
TL;DR: There is evidence consistent with both main effect and main effect models for social support, but each represents a different process through which social support may affect well-being.
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Oxidative stress, antioxidants and stress tolerance
TL;DR: Key steps of the signal transduction pathway that senses ROIs in plants have been identified and raise several intriguing questions about the relationships between ROI signaling, ROI stress and the production and scavenging ofROIs in the different cellular compartments.
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Fitness Effects on the Cognitive Function of Older Adults: A Meta-Analytic Study
TL;DR: Fitness training was found to have robust but selective benefits for cognition, with the largest fitness-induced benefits occurring for executive-control processes.