Obesity and impaired metabolic health in patients with COVID-19.
TLDR
Preliminary data suggest that people with obesity are at increased risk of severe COVID-19, but as data on metabolic parameters in patients with CO VID-19 are scarce, increased reporting is needed to improve understanding of the drug and the care of affected patients.Abstract:
Preliminary data suggest that people with obesity are at increased risk of severe COVID-19. However, as data on metabolic parameters (such as BMI and levels of glucose and insulin) in patients with COVID-19 are scarce, increased reporting is needed to improve our understanding of COVID-19 and the care of affected patients.read more
Citations
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Individuals with obesity and COVID-19: A global perspective on the epidemiology and biological relationships.
Barry M. Popkin,Barry M. Popkin,Shufa Du,William R. Green,Melinda A. Beck,Taghred Algaith,Christopher H. Herbst,Reem Alsukait,Reem Alsukait,Mohammed Alluhidan,Nahar Alazemi,Meera Shekar +11 more
TL;DR: Mechanistic pathways for individuals with obesity are presented in depth for factors linked with COVID‐19 risk, severity and their potential for diminished therapeutic and prophylactic treatments among these individuals.
Journal ArticleDOI
Platelet gene expression and function in patients with COVID-19.
Bhanu Kanth Manne,Frederik Denorme,Elizabeth A. Middleton,Irina Portier,Jesse W. Rowley,Chris Stubben,Aaron C. Petrey,Neal D. Tolley,Li Guo,Mark J. Cody,Andrew S. Weyrich,Christian C. Yost,Matthew T. Rondina,Robert A. Campbell +13 more
TL;DR: It is demonstrated that SARS-CoV-2 infection is associated with platelet hyperreactivity, which may contribute to COVID-19 pathophysiology.
Journal ArticleDOI
Why does COVID-19 disproportionately affect older people?
TL;DR: The molecular differences between young, middle-aged and older people that may explain why COVID-19 is a mild illness in some but life-threatening in others are presented and treatments that could increase the survival of older people are discussed.
Journal ArticleDOI
T cell responses in patients with COVID-19.
Zeyu Chen,E. John Wherry +1 more
TL;DR: Early reports of the T cell responses observed in patients with COVID-19 are summarized, emphasizing how different immune response characteristics in different patients may reflect a spectrum of disease phenotypes.
Journal ArticleDOI
Obesity and Mortality Among Patients Diagnosed With COVID-19: Results From an Integrated Health Care Organization.
Sara Y. Tartof,Lei Qian,Vennis Hong,Rong Wei,Ron F. Nadjafi,Heidi Fischer,Zhuoxin Li,Sally F. Shaw,Susan L. Caparosa,Claudia Nau,Tanmai Saxena,Gunter Rieg,Bradley Ackerson,Adam L. Sharp,Jacek Skarbinski,Tej K. Naik,Sameer B. Murali +16 more
TL;DR: This study examines the association between obesity and death 21 days after diagnosis of COVID-19 among patients who receive care in an integrated health care system, accounting for obesity-related comorbidities and sociodemographic factors.
References
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Journal ArticleDOI
Meta-Analysis: A Constantly Evolving Research Integration Tool
TL;DR: The four articles in this special section onMeta-analysis illustrate some of the complexities entailed in meta-analysis methods and contributes both to advancing this methodology and to the increasing complexities that can befuddle researchers.
Journal ArticleDOI
Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention
Zunyou Wu,Jennifer M. McGoogan +1 more
TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
Journal ArticleDOI
Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy.
Giacomo Grasselli,Giacomo Grasselli,Alberto Zangrillo,Alberto Zanella,Alberto Zanella,Massimo Antonelli,Massimo Antonelli,Luca Cabrini,Antonio Castelli,Danilo Cereda,Antonio Coluccello,Giuseppe Foti,Roberto Fumagalli,Giorgio Antonio Iotti,Nicola Latronico,Luca Lorini,Stefano Merler,Giuseppe Natalini,Alessandra Piatti,Marco Ranieri,Anna Mara Scandroglio,Enrico Storti,Maurizio Cecconi,Antonio Pesenti,Antonio Pesenti +24 more
TL;DR: Patients with coronavirus disease 2019 (COVID-19) requiring treatment in an intensive care unit (ICU) in the Lombardy region of Italy were characterized, including data on clinical management, respiratory failure, and patient mortality.
Journal ArticleDOI
Covid-19 in Critically Ill Patients in the Seattle Region - Case Series.
Pavan K. Bhatraju,Bijan J Ghassemieh,Michelle Nichols,Richard Kim,Keith R. Jerome,Arun K. Nalla,Alexander L. Greninger,Sudhakar Pipavath,Mark M Wurfel,Laura Evans,Patricia M Kritek,T. Eoin West,Andrew M Luks,Anthony Gerbino,Christopher R. Dale,Jason D Goldman,D. Shane O’Mahony,Carmen Mikacenic +17 more
TL;DR: During the first 3 weeks of the Covid-19 outbreak in the Seattle area, the most common reasons for admission to the ICU were hypoxemic respiratory failure leading to mechanical ventilation, hypotension requiring vasopressor treatment, or both.
Journal ArticleDOI
High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Requiring Invasive Mechanical Ventilation.
Arthur Simonnet,Mikael Chetboun,Julien Poissy,Violeta Raverdy,Jerome Noulette,Alain Duhamel,Julien Labreuche,Daniel Mathieu,François Pattou,Mercé Jourdain +9 more
TL;DR: The COVID‐19 pandemic is rapidly spreading worldwide, notably in Europe and North America where obesity is highly prevalent and the relation between obesity and severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) has not been fully documented.
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