Obstetric and perinatal outcomes after either fresh or thawed frozen embryo transfer: an analysis of 112,432 singleton pregnancies recorded in the Human Fertilisation and Embryology Authority anonymized dataset
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TLDR
The findings of low birth and very low birth weight after thawed frozen embryo transfer are consistent with the literature and provide reassurance regarding the outcome of pregnancies after frozen embryo transfers, however, they highlight the possibility of high birth weight in these babies.About:
This article is published in Fertility and Sterility.The article was published on 2016-12-01 and is currently open access. It has received 124 citations till now. The article focuses on the topics: Low birth weight & Birth weight.read more
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Journal ArticleDOI
Is frozen embryo transfer better for mothers and babies? Can cumulative meta-analysis provide a definitive answer?
Abha Maheshwari,Shilpi Pandey,Edwin Amalraj Raja,Ashalatha Shetty,Mark Hamilton,Siladitya Bhattacharya +5 more
TL;DR: The results of this cumulative meta-analysis of obstetric and perinatal complications in singleton pregnancies following the transfer of frozen thawed and fresh embryos generated through in-vitro fertilisation confirm that the decreased risks of small for gestational age, low birth weight and preterm delivery and increased risks of large for Gestational age and high birth weight associated with pregnancies conceived from frozen embryos have been consistent in terms of direction and magnitude of effect over several years.
Journal ArticleDOI
Transfer of Fresh versus Frozen Embryos in Ovulatory Women
Yuhua Shi,Yun Sun,Cuifang Hao,Heping Zhang,Daimin Wei,Yunshan Zhang,Yimin Zhu,Xiaohui Deng,Xiujuan Qi,Hong Li,Xiang Ma,Haiqin Ren,Yaqin Wang,Dan Zhang,Bo Wang,Fenghua Liu,Qiongfang Wu,Ze Wang,Haiyan Bai,Yuan Li,Yi Zhou,Mei Sun,Hong Liu,Jing Li,Lin Zhang,Xiaoli Chen,Songying Zhang,Xiaoxi Sun,Richard S. Legro,Zi-Jiang Chen +29 more
TL;DR: The live‐birth rate did not differ significantly between fresh‐embryo transfer and frozen‐embrieso transfer among ovulatory women with infertility, but frozen‐embroidered transfer resulted in a lower risk of the ovarian hyperstimulation syndrome.
Journal ArticleDOI
The health of children conceived by ART: 'the chicken or the egg?'
Sine Berntsen,Viveca Söderström-Anttila,Ulla-Britt Wennerholm,Hannele Laivuori,Anne Loft,Nan B. Oldereid,Liv Bente Romundstad,Christina Bergh,Anja Pinborg +8 more
TL;DR: Risks for short- and long-term health in ART singletons are summarized and if the increased health risks are associated with intrinsic maternal or paternal factors related to subfertility or to the ART treatments per se is discussed.
Journal ArticleDOI
Pregnancy-related complications and perinatal outcomes resulting from transfer of cryopreserved versus fresh embryos in vitro fertilization: a meta-analysis.
TL;DR: Pregnancies resulting from FET were associated with lower relative risks of placenta previa, placental abruption, low birth weight, very preterm birth, small for gestational age, and perinatal mortality than fresh ET, some differences that are attributed to the increased risks of pregnancy-induced hypertension, large for gestations, and postpartum hemorrhage.
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Supraphysiologic estradiol is an independent predictor of low birth weight in full-term singletons born after fresh embryo transfer
Nigel Pereira,Rony T. Elias,Paul J. Christos,Allison C. Petrini,K. Hancock,Jovana P. Lekovich,Zev Rosenwaks +6 more
TL;DR: The results suggest that E2 > 2500 pg/ml is an independent predictor for LBW in full-term singletons born to normal responder patients undergoing fresh IVF-ET cycles, and emphasize the importance of minimizing the supraphysiologic elevations of E2 levels during ovarian stimulation in fresh IVFs.
References
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Journal ArticleDOI
Fresh embryo transfer versus frozen embryo transfer in in vitro fertilization cycles: a systematic review and meta-analysis.
TL;DR: There is evidence that IVF outcomes may be improved by performing FET compared with fresh embryo transfer, and this could be explained by a better embryo-endometrium synchrony achieved with endometrium preparation cycles.
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Obstetric and perinatal outcomes in singleton pregnancies resulting from the transfer of frozen thawed versus fresh embryos generated through in vitro fertilization treatment: a systematic review and meta-analysis
TL;DR: Although fresh ET is the norm in IVF, results of this systematic review of observational studies suggest that pregnancies arising from the transfer of frozen thawed IVF embryos seem to have better obstetric and perinatal outcomes.
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International Committee for Monitoring Assisted Reproductive Technologies world report: Assisted Reproductive Technology 2008, 2009 and 2010
Silke Dyer,Georgina M. Chambers,J. de Mouzon,K.G. Nygren,Fernando Zegers-Hochschild,Ragaa T. Mansour,Osamu Ishihara,Manish Banker,G.D. Adamson +8 more
TL;DR: Global utilization and effectiveness remained relatively constant despite marked variations among countries, while the rate of single and frozen embryo transfers (FETs) increased with a concomitant slight reduction in multiple birth rates.
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Perinatal outcomes of children born after frozen-thawed embryo transfer: a Nordic cohort study from the CoNARTaS group
Ulla-Britt Wennerholm,Anna-Karina Aaris Henningsen,Liv Bente Romundstad,Christina Bergh,Anja Pinborg,Rolv Skjærven,Julie Lyng Forman,Mika Gissler,Karl-Gösta Nygren,Aila Tiitinen +9 more
TL;DR: Singletons born after FET have a better perinatal outcome compared with singletons Born after fresh IVF and ICSI as regards low birthweight (LBW) and preterm birth (PTB), but a worse per inatal outcomeCompared with children conceived after spontaneous conception.
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Cycle regimens for frozen-thawed embryo transfer
TL;DR: There was no evidence of a difference in multiple pregnancy rates between women in natural cycles and those in HT FET cycle, and very low-quality evidence suggested that women innatural cycles (without HCG trigger) may have higher ongoing pregnancy rates.