Journal ArticleDOI
On the mechanism of ethanol-induced fatty liver and its reversibility by adenosine.
Rolando Hernández-Muñoz,Aida Santamaría,J. Adolfo García-Sáinz,Enrique Piña,Victoria Chagoya de Sánchez +4 more
TLDR
It is suggested that adenosine ameliorated the ethanol-induced fatty liver through an increased utilization of reducing equivalents by the mitochondria and an interdependence of these effects is proposed and discussed.About:
This article is published in Archives of Biochemistry and Biophysics.The article was published on 1978-09-01. It has received 39 citations till now. The article focuses on the topics: Fatty liver & Adenine nucleotide.read more
Citations
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Journal ArticleDOI
Ethanol-induced hyperuricemia: evidence for increased urate production by activation of adenine nucleotide turnover.
Jason Faller,Irving H. Fox +1 more
TL;DR: The data indicate that ethanol increases urate synthesis by enhancing the turnover of adenine nucleotides in patients with gout through increased production and decreased excretion of uric acid.
Book
Hepatic Circulation: Physiology and Pathophysiology
TL;DR: The development of knowledge of the hepatic vasculature is presented from a historical perspective with modern concepts summarized based on the perspective of the author’s four decades of devotion to this most marvelous of organs.
Journal ArticleDOI
Adenosine partially prevents cirrhosis induced by carbon tetrachloride in rats.
TL;DR: Adenosine administration was tested in rats with carbon tetrachloride–induced hepatic fibrosis and was able to partially prevent the enlargement of liver and spleen induced by the toxin, accompanied by a 50% reduction of the liver collagen deposition and preservation of content of glycosaminoglycans.
Journal ArticleDOI
Quantitative analysis of intermediary metabolism in rat hepatocytes incubated in the presence and absence of ethanol with a substrate mixture including ketoleucine.
J M Baranyai,J. J. Blum +1 more
TL;DR: Ketoleucine was utilized at a rate comparable to that reported by others in perfused liver and entered the mitochondrial pool of acetyl-CoA directly associated with ketone body formation, and several effects related to the increased NADH/NAD+ ratio were observed.
Journal ArticleDOI
Dietary arachidonic acid reduces fatty liver, increases diet consumption and weight gain in ethanol-fed rats.
TL;DR: The diet consumption and body wts of rats in the AA+ group were significantly greater than those of rats fed alcohol without the 20∶4 supplement (AA−), and livers from rats in that group were as large as those from Rats in control groups (CA+, CA−).
References
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Journal ArticleDOI
The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers.
TL;DR: An electrostatic spray apparatus and method for spraying electrically conductive coating materials on a continuous basis from an electrically grounded bulk coating supply.
Journal ArticleDOI
Microdetermination of long-chain fatty acids in plasma and tissues.
Vincent P. Dole,Hans Meinertz +1 more
TL;DR: The present paper outlines the phase relations of the ternary system at room temperature, gives partition coefficients of fatty acids and other materials in a standard two-phase extraction mixture, discusses use of the system in countercurrent estraction, and outlines some modifications of the original procedure that have developed during five years of analytical work in this laboratory.
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Micromethod for the direct determination of serum triglycerides.
E. Van Handel,D.B. Zilversmit +1 more
TL;DR: A microprocedure for the direct determination of triglyceride concentrations in biologic specimens is presented and depends on the quantitative removal of phosphatides from the sample and the subsequent determination of esterified glycerol.
Journal ArticleDOI
Hormone-fuel interrelationships during fasting.
George F. Cahill,M G Herrera,A P Morgan,J S Soeldner,Jurgen Steinke,P L Levy,G A Reichard,D M Kipnis +7 more
TL;DR: Over 50 years ago, Benedict published his extensive monograph on the metabolism of fasting in man, in which he demonstrated that carbohydrate stores provide a small but significant component of the body's fuel for only the first few days.