Journal ArticleDOI
Orodispersible drug formulations for children and elderly.
Marta Slavkova,Jörg Breitkreutz +1 more
TLDR
The review reports the recent advances, existing and upcoming products, and the significance of formulating patient-friendly oral dosage forms on the basis of regulatory guidelines and pharmacopoeial monographs to foster the development of innovative orodispersible drug dosage forms.About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2015-07-30. It has received 175 citations till now.read more
Citations
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Journal ArticleDOI
3D printed orodispersible films with Aripiprazole
Witold Jamróz,Mateusz Kurek,Ewelina Łyszczarz,Joanna Szafraniec,Justyna Knapik-Kowalczuk,Karolina Syrek,Marian Paluch,Renata Jachowicz +7 more
TL;DR: Fused deposition modelling is suitable technique and polyvinyl alcohol is applicable polymer for orodispersible films preparation and transition of aripiprazole into amorphous state during film preparation using 3D printing technique is confirmed.
Journal ArticleDOI
The Application of 3D Printing in the Formulation of Multilayered Fast Dissolving Oral Films
Touraj Ehtezazi,Marwan Algellay,Yamir Islam,Matthew C. Roberts,Nicola M. Dempster,Satyajit D. Sarker +5 more
TL;DR: This study provides proof-of-concept for the manufacturing of FDFs by using 3D printing for fast-dissolving oral films with active ingredient stability during film preparation process.
Journal ArticleDOI
Personalized orodispersible films by hot melt ram extrusion 3D printing
Umberto M. Musazzi,Francesca Selmin,Marco Aldo Ortenzi,Garba Khalid Mohammed,Silvia Franzè,Paola Minghetti,Francesco Cilurzo +6 more
TL;DR: This work demonstrates the feasibility of the extemporaneous preparation of maltodextrins orodispersible films (ODF) by hot‐melt ram‐extrusion 3D printing, demonstrating the suitability of the proposed technology.
Journal ArticleDOI
Development and evaluation of an oral fast disintegrating anti-allergic film using hot-melt extrusion technology
Manjeet B. Pimparade,Anh Q. Vo,Abhijeet Maurya,Jungeun Bae,Joseph T. Morott,Xin Feng,Dong Wuk Kim,Vijay I. Kulkarni,Roshan V. Tiwari,K. Vanaja,Reena Murthy,H.N. Shivakumar,D. Neupane,Sanjay R. Mishra,S. N. Murthy,Michael A. Repka +15 more
TL;DR: The main objective of this novel study was to develop chlorpheniramine maleate orally disintegrating films (ODF) using hot‐melt extrusion technology and evaluate the characteristics of the formulation using in vitro and in vivo methods.
Journal ArticleDOI
Oromucosal film preparations: points to consider for patient centricity and manufacturing processes.
Raphael Krampe,J. Carolina Visser,Henderik W. Frijlink,Joerg Breitkreutz,Herman J. Woerdenbag,Maren Preis +5 more
TL;DR: In this review, technological issues such as viscosity of the Casting liquid, mechanical properties of the film, upscaling and the stability of the casting solution and produced films will be discussed and patient-related problems like appearance, mucosal irritation, taste, drug load, safety and biopharmaceutics are described.
References
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Journal ArticleDOI
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: An Explanation and Elaboration of the PRISMA Statement is presented and updated guidelines for the reporting of systematic reviews and meta-analyses are presented.
Journal ArticleDOI
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: This Explanation and Elaboration document explains the meaning and rationale for each checklist item and includes an example of good reporting and, where possible, references to relevant empirical studies and methodological literature.
Journal ArticleDOI
Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children
Gregory L. Kearns,Susan M. Abdel-Rahman,Sarah W. Alander,Douglas L. Blowey,J. Steven Leeder,Ralph E. Kauffman +5 more
TL;DR: This review examines the developmental changes that profoundly affect the responses of children to medications and related therapies in the very young.
Journal ArticleDOI
Drug-delivery products and the Zydis fast-dissolving dosage form.
TL;DR: Many patients find it difficult to swallow tablets and hard gelatin capsules and do not take their medication as prescribed, but such problems can be resolved by means of the Zydis dosage form which does not require water to aid swallowing.
Journal ArticleDOI
Advances in orodispersible films for drug delivery.
TL;DR: The magnitude of variants of ODF technology and the advantages over conventional dosage forms promise more applications and more marketed products with ODFs in the near future.