Journal ArticleDOI
Oxidation of thiol compounds by molecular oxygen in aqueous solutions
TLDR
In this paper, side self-oxidation of thiols was studied and it was found that these reactions in neutral and alkaline solutions are induced by impurities of variable-valence metals.Abstract:
Side self-oxidation of thiols was studied. It was found that these reactions in neutral and alkaline solutions are induced by impurities of variable-valence metals. The ability of transition metals to catalyze oxidation of thiols changes in the order Cu > Mn > Fe > Ni ≫ Co. The plot of the self-oxidation rate vs. pH passes through a maximum whose position on the pH scale depends on both the nature of metal and the structure of the thiol oxidized. For thiols having different structures, the kinetic orders in reactions catalyzed by copper ions differently vary with pH, which is apparently associated with the formation of complexes possessing different catalytic activity.read more
Citations
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Journal ArticleDOI
Quantification of Thiols and Disulfides
Jakob R. Winther,Colin Thorpe +1 more
TL;DR: The toolbox available to the experimentalist for the chemical determination of thiols and disulfides is surveyed, with a focus on the key chemical aspects of current methodology, together with identifying potential difficulties inherent in their experimental implementation.
Journal ArticleDOI
Native Chemical Ligation and Extended Methods: Mechanisms, Catalysis, Scope, and Limitations
Vangelis Agouridas,Ouafâa El Mahdi,Vincent Diemer,Marine Cargoët,Jean-Christophe Monbaliu,Oleg Melnyk +5 more
TL;DR: The most relevant properties of peptide thioesters, Cys peptides, and common solvents, reagents, additives, and catalysts used for these ligations are presented and the various thiol-based auxiliaries and thiol or selenol amino acid surrogates that have been developed so far are discussed.
Journal ArticleDOI
An introduction to methods for analyzing thiols and disulfides: Reactions, reagents, and practical considerations
Rosa E. Hansen,Jakob R. Winther +1 more
TL;DR: In thiol–disulfide exchange reactions, it is important to consider reaction rate and the equilibrium constants between various thiol and disulfide species, because the thiolate anion is the reactive species, these properties are particularly sensitive to thiol pKa values.
Journal ArticleDOI
Generation of reactive oxygen species mediated by humic-like substances in atmospheric aerosols.
Peng Lin,Jian Zhen Yu +1 more
TL;DR: HULIS was found to be the major redox active constituent of the water-extractable organic fraction in PM and it is plausible that HULIS contains reversible redox sites, thereby serving as electron carriers to catalyze the formation of ROS.
Journal ArticleDOI
One-step reduction of graphene oxide with l-glutathione
TL;DR: In this article, a green and facile approach to produce graphene by using an environmentally friendly reagent, namely, l-glutathione as a reducing agent, was developed, and the resulting graphene was characterized using a range of analytical techniques.
References
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Journal ArticleDOI
Tissue sulfhydryl groups
TL;DR: A water-soluble (at pH 8) aromatic disulfide [5,5′-dithiobis(2-nitrobenzoic acid] has been synthesized and shown to be useful for determination of sulfhydryl groups.
Journal ArticleDOI
Aconitase as iron-sulfur protein, enzyme, and iron-regulatory protein
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Book ChapterDOI
Copper protein structures.
TL;DR: It may be that the copper-containing Greek key proteins represent a very small evolutionary niche, and the apoproteins are clearly stable without metals; there are examples other than immunoglobulins of Greek key folds.