Parcellation of the human substantia nigra based on anatomical connectivity to the striatum
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TLDR
It is shown that tractography can be used to parcellate the SN/VTA into anatomically plausible and behaviourally meaningful compartments, an approach that may help future studies to provide a more fine-grained synopsis of pathological changes in the dopaminergic midbrain and their functional impact.About:
This article is published in NeuroImage.The article was published on 2013-11-01 and is currently open access. It has received 60 citations till now. The article focuses on the topics: Ventral tegmental area & Ventral striatum.read more
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Journal ArticleDOI
Resting state networks distinguish human ventral tegmental area from substantia nigra.
Vishnu P. Murty,Maheen Shermohammed,David V. Smith,R. McKell Carter,Scott A. Huettel,R. Alison Adcock +5 more
TL;DR: A method for reliably defining SN and VTA in humans at conventional MRI resolution was developed, and a probabilistic atlas of the VTA, SN, and the dopaminergic midbrain region was constructed from individual hand-drawn ROIs, validating the utility of this probabilists atlas for future research.
Journal ArticleDOI
Connectivity derived thalamic segmentation in deep brain stimulation for tremor
Harith Akram,Viswas Dayal,Philipp Mahlknecht,Philipp Mahlknecht,Dejan Georgiev,Jonathan Hyam,Thomas Foltynie,Patricia Limousin,Enrico De Vita,Enrico De Vita,Marjan Jahanshahi,John Ashburner,Timothy E.J. Behrens,Timothy E.J. Behrens,Marwan Hariz,Marwan Hariz,Ludvic Zrinzo +16 more
TL;DR: It is concluded that probabilistic tractography techniques can be used to segment the VL and VP thalamus based on cortical and cerebellar connectivity in patients that will undergo thalamic DBS for tremor.
Journal ArticleDOI
Alterations in amygdala-prefrontal circuits in infants exposed to prenatal maternal depression.
Jonathan Posner,Jiook Cha,Jiook Cha,Amy Krain Roy,Bradley S. Peterson,Ravi Bansal,Hanna C. Gustafsson,Elizabeth Raffanello,Jay A. Gingrich,Jay A. Gingrich,Catherine Monk,Catherine Monk +11 more
TL;DR: This is the first study to directly associate infant MRI measures with a behavior—fetal heart rate response, and supports hypotheses that PMD-associated variations in the development of amygdala–PFC circuits are relevant for future neurobehavioral maturation.
Journal ArticleDOI
Increased Default Mode Network Connectivity in Individuals at High Familial Risk for Depression
Jonathan Posner,Jonathan Posner,Jiook Cha,Jiook Cha,Zhishun Wang,Zhishun Wang,Ardesheer Talati,Ardesheer Talati,Virginia Warner,Virginia Warner,Andrew J. Gerber,Andrew J. Gerber,Bradley S. Peterson,Myrna M. Weissman,Myrna M. Weissman +14 more
TL;DR: It is suggested that DMN and DMN-CEN connectivity differ in those at high vs low risk for depression and thus suggest potential biomarkers for identifying individuals at risk for developing MDD.
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Separate mesocortical and mesolimbic pathways encode effort and reward learning signals.
TL;DR: It is shown that motivationally relevant stimulus features are learned in parallel dopaminergic pathways, with formation of an integrated utility signal at choice, highlighting how the brain parses parallel learning demands.
References
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Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain
Nathalie Tzourio-Mazoyer,B. Landeau,D. Papathanassiou,Fabrice Crivello,Octave Etard,Nicolas Delcroix,Bernard Mazoyer,Marc Joliot +7 more
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