Patient blood management during cardiac surgery: do we have enough evidence for clinical practice?
Marco Ranucci,Solomon Aronson,Wulf Dietrich,Cornelius M. Dyke,Axel Hofmann,Keyvan Karkouti,Marcel Levi,Gavin J. Murphy,Frank W. Sellke,Linda Shore-Lesserson,Christian von Heymann +10 more
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TLDR
A large body of evidence indicates that transfusion of blood products per se may be associated with increased morbid-ity and mortality after cardiac operations.About:
This article is published in The Journal of Thoracic and Cardiovascular Surgery.The article was published on 2011-08-01 and is currently open access. It has received 72 citations till now. The article focuses on the topics: Blood transfusion & Blood management.read more
Citations
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Journal ArticleDOI
2017 EACTS/EACTA Guidelines on patient blood management for adult cardiac surgery.
Domenico Pagano,Milan Milojevic,Michael I. Meesters,Umberto Benedetto,Daniel Bolliger,Christian von Heymann,Anders Jeppsson,Andreas Koster,Ruben L.J. Osnabrugge,Marco Ranucci,Hanne Berg Ravn,Alexander B.A. Vonk,Alexander Wahba,Christa Boer +13 more
Journal ArticleDOI
Universal definition of perioperative bleeding in adult cardiac surgery.
Cornelius M. Dyke,Solomon Aronson,Wulf Dietrich,Axel Hofmann,Keyvan Karkouti,Keyvan Karkouti,Marcel Levi,Gavin J. Murphy,Frank W. Sellke,Linda Shore-Lesserson,Christian von Heymann,Marco Ranucci +11 more
TL;DR: The proposed universal definition for perioperative bleeding (UDPB) in adult cardiac surgery provides a precise classification of bleeding that is useful in everyday practice as well as in clinical research.
Journal ArticleDOI
2017 EACTS/EACTA Guidelines on patient blood management for adult cardiac surgery.
Christa Boer,Michael I. Meesters,Milan Milojevic,Umberto Benedetto,Daniel Bolliger,Christian von Heymann,Anders Jeppsson,Andreas Koster,Ruben L.J. Osnabrugge,Marco Ranucci,Hanne Berg Ravn,Alexander B.A. Vonk,Alexander Wahba,Domenico Pagano +13 more
TL;DR: Authors/Task Force Members: Christa Boer (EACTA Chairperson) and Michael I. Meesters (Netherlands), Milan Milojevic (N Netherlands), Umberto Benedetto (UK), Daniel Bolliger (Switzerland), Christian von Heymann (Germany), Anders Jeppsson (Sweden), Andreas Koster (Germany).
Journal ArticleDOI
Major Bleeding, Transfusions, and Anemia: The Deadly Triad of Cardiac Surgery
TL;DR: Major bleeding is per se a risk factor for operative mortality, however, its deleterious effects are strongly enhanced by RBC transfusions and, to a lesser extent, preoperative anemia.
Journal ArticleDOI
Routine use of viscoelastic blood tests for diagnosis and treatment of coagulopathic bleeding in cardiac surgery: updated systematic review and meta-analysis.
TL;DR: Routine use of viscoelastic point-of-care tests did not improve important clinical outcomes beyond transfusion in adults undergoing cardiac surgery and the quality of the evidence was low or very low for all estimated outcomes.
References
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Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes
Stephen D. Wiviott,Eugene Braunwald,Carolyn H. McCabe,Gilles Montalescot,Witold Rużyłło,Shmuel Gottlieb,Franz Joseph Neumann,Diego Ardissino,Stefano De Servi,Sabina A. Murphy,Jeffrey S. Riesmeyer,Govinda Weerakkody,C. Michael Gibson,Elliott M. Antman +13 more
TL;DR: In patients with acute coronary syndromes with scheduled percutaneous coronary intervention, prasugrel therapy was associated with significantly reduced rates of ischemic events, including stent thrombosis, but with an increased risk of major bleeding, including fatal bleeding.
Journal ArticleDOI
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation.
Salim Yusuf,Zhao F,Shamir R. Mehta,Susan Chrolavicius,Gianni Tognoni,K K Fox,Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators +6 more
TL;DR: The antiplatelet agent clopidogrel has beneficial effects in patients with acute coronary syndromes without ST-segment elevation, however, the risk of major bleeding is increased among patients treated with clopIDogrel.
Journal ArticleDOI
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group.
Paul C. Hébert,George A. Wells,Morris A. Blajchman,John C. Marshall,Claudio Martin,Giuseppe Pagliarello,Martin Tweeddale,Irwin Schweitzer,Elizabeth Yetisir +8 more
TL;DR: A restrictive strategy of red-cell transfusion is at least as effective as and possibly superior to a liberal transfusion strategy in critically ill patients, with the possible exception of patients with acute myocardial infarction and unstable angina.
Journal ArticleDOI
A comparison of albumin and saline for fluid resuscitation in the intensive care unit
TL;DR: In patients in the ICU, use of either 4 percent albumin or normal saline for fluid resuscitation results in similar outcomes at 28 days, with no significant differences between the groups.
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