Book ChapterDOI
Pediatric Brain Tumors: Viewpoint—Chemotherapy
Nathan Robison
- pp 439-443
TLDR
Stereotactic radiosurgery (SRS) has advantages over other therapeutic modalities in certain settings and has a role in the management of pediatric brain tumors, however, that role is limited by the propensity of pediatric neural tumors to disseminate along cerebrospinal fluid pathways or to infiltrate surrounding brain.Abstract:
Pediatric brain tumors encompass a heterogeneous group of diseases. For many tumors, such as low-grade glioma and standard-risk medulloblastoma, the long-term survival rate is high. Clinical investigation for these diseases in recent decades has focused on addressing late effects of therapy, in particular the neurocognitive effects of cranial radiation. Chemotherapy has been used effectively in many settings to delay radiation, to reduce radiation dose and volume, or to replace cranial irradiation entirely. For other tumors, diffuse intrinsic pontine glioma most notoriously, prognosis remains abysmal and currently available treatments are primarily palliative. Stereotactic radiosurgery (SRS) has advantages over other therapeutic modalities in certain settings and has a role in the management pediatric brain tumors. That role is limited, however, by the propensity of pediatric neural tumors to disseminate along cerebrospinal fluid (CSF) pathways or to infiltrate surrounding brain.read more
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Head start
TL;DR: In el últ ima década, han aumentado los casos de los niños criados por sus abuelos. as mentioned in this paper reportó algunos of los ef ectos de dicho cuidado en los nietos, así como las necesidades que son importantes para apoyar a los abuelo cuidadores, e inf ormación sobre los recursos que existen a su disposición.
References
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