Journal ArticleDOI
Persistent psychosis following the use of Spice.
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TLDR
Three patients with severe, persisting, psychotic symptoms and regular SCCP use for 3–4 weeks prior to admission are presented, who required inpatient stabilization with neuroleptic medication.About:
This article is published in Schizophrenia Research.The article was published on 2011-08-01. It has received 57 citations till now.read more
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Synthetic cannabinoids: Epidemiology, pharmacodynamics, and clinical implications
Marisol S. Castaneto,David A. Gorelick,Nathalie A. Desrosiers,Nathalie A. Desrosiers,Rebecca L. Hartman,Rebecca L. Hartman,Sandrine Pirard,Marilyn A. Huestis +7 more
TL;DR: A comprehensive review, based on a systematic electronic literature search, of SC epidemiology and pharmacology and their clinical implications is presented, showing in vitro and animal in vivo studies show SC pharmacological effects 2-100 times more potent than THC.
Journal ArticleDOI
A systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment
TL;DR: To identify systematically the scientific reports of adverse events associated with the consumption of SCs in the medical literature and poison centre data, this work searched online databases and manually searched reference lists up to December 2014 to identify eligible studies.
Journal ArticleDOI
Spicing things up: synthetic cannabinoids
TL;DR: There is an urgent need for better research on the effects of synthetic cannabinoids to help clinicians manage adverse events and to better understand cannabinoid pharmacology in humans.
Journal Article
Pharmacology, Toxicology, and Adverse Effects of Synthetic Cannabinoid Drugs
Susan M. R. Gurney,Karen S. Scott,S. L. Kacinko,Brandon C. Presley,Barry K. Logan,Willow Grove +5 more
TL;DR: There is growing toxicological and pharmacological evidence of impairment, psychosis, tissue injury, and isolated deaths attributable to this emerging class of drugs.
Journal ArticleDOI
“Spiceophrenia”: a systematic overview of “Spice”‐related psychopathological issues and a case report
Duccio Papanti,Fabrizio Schifano,Giulia Botteon,F. Bertossi,Jason Mannix,Daniela Vidoni,Matteo Impagnatiello,Elisabetta Pascolo-Fabrici,Tommaso Bonavigo +8 more
TL;DR: A systematic review of the related literature and a case report are presented, which seems to highlight the existence of a possible association between SC use and psychosis.
References
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Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis
TL;DR: Hair samples were analysed to examine levels of Δ9-THC and CBD in 140 individuals and three clear groups emerged: ’THC only’, ‘THC+CBD’ and those with no cannabinoid in hair, which provides evidence of the divergent properties of cannabinoids.
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Synthetic cannabinoid JWH-018 and psychosis: An explorative study
TL;DR: It seems likely that JWH-018 can precipitate psychosis in vulnerable individuals and people with risk factors for psychosis should be counseled against using synthetic cannabinoids.
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The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes
Helge H. Müller,Wolfgang Sperling,Martin Köhrmann,Hagen B. Huttner,Johannes Kornhuber,J. M. Maler +5 more
TL;DR: This case presents the case of a 25 year old man who had a history of cannabis induced recurrent psychotic episodes and an acute reactivation of symptoms after abuse of the synthetic cannabinoid “Spice”.