Pharmaceutical and biomaterial engineering via electrohydrodynamic atomization technologies
Prina Mehta,Rita Haj-Ahmad,Manoochehr Rasekh,Muhammad Arshad,Ashleigh Smith,Susanna M. van der Merwe,Xiang Li,Ming Wei Chang,Zeeshan Ahmad +8 more
TLDR
Electrohydrodynamic atomization technologies are rapidly emerging as promising candidates to address key healthcare challenges as well as established advances in the field of pharmaceutical and biomaterial applications.About:
This article is published in Drug Discovery Today.The article was published on 2017-01-01 and is currently open access. It has received 101 citations till now.read more
Citations
More filters
Journal ArticleDOI
Electrosprayed hydrophilic nanocomposites coated with shellac for colon-specific delayed drug delivery
TL;DR: A structural nanocomposite (P2) consisting of tamoxifen citrate (TC) and polyvinylpyrrolidone (PVP) (2:8, w:w) as core and shellac as shell was designed and fabricated using a modified coaxial electrospraying process as mentioned in this paper.
Journal ArticleDOI
Electrospun tri-layer nanodepots for sustained release of acyclovir
TL;DR: In this paper, a trilayer nanodepot with a drug reservoir was built into a core-shell nanofiber and a modified triaxial electrospinning was implemented to prepare the trillayer depots F2 using cellulose acetate and acyclovir as polymer matrix and active ingredient, respectively.
Journal ArticleDOI
Tunable drug release from nanofibers coated with blank cellulose acetate layers fabricated using tri-axial electrospinning.
TL;DR: In this study, novel core-shell nanostructures were fabricated through a modified triaxial electrospinning process that comprised a drug-protein nanocomposite coated with a thin cellulose acetate shell and allowed us to precisely manipulate the drug release over a time period in a tunable manner.
Journal ArticleDOI
Tunable zero-order drug delivery systems created by modified triaxial electrospinning
TL;DR: In this paper, a modified triaxial electrospinning process was successfully developed to tune drug release from nanoscale formulations in order to accurately control a material's structure, and in turn its functional performance.
Journal ArticleDOI
Scale-up of electrospinning technology: Applications in the pharmaceutical industry.
Panna Vass,Edina Szabó,András Domokos,Edit Hirsch,Dorián László Galata,Balázs Farkas,Balázs Démuth,Sune K. Andersen,Tamás Vigh,Geert Verreck,György Marosi,Zsombor Kristóf Nagy +11 more
TL;DR: This article covers the various ES technologies developed for scaled-up fiber production with an emphasis on pharmaceutically relevant examples and compares them in terms of their basic principles, advantages, and limitations.
References
More filters
Journal ArticleDOI
High-resolution electrohydrodynamic jet printing
Jang Ung Park,Matthew T. Hardy,Seong Jun Kang,Seong Jun Kang,Kira Barton,Kurt Adair,Deepkishore Mukhopadhyay,Chang Young Lee,Michael S. Strano,Andrew G. Alleyne,John G. Georgiadis,Placid M. Ferreira,John A. Rogers +12 more
TL;DR: Key aspects of the physics of this approach, which has some features in common with related but comparatively low-resolution techniques for graphic arts, are revealed through direct high-speed imaging of the droplet formation processes.
Journal ArticleDOI
Micro/Nano Encapsulation via Electrified Coaxial Liquid Jets
Ignacio G. Loscertales,Antonio Barrero,I. Guerrero,R. Cortijo,Manuel Marquez,Manuel Marquez,Alfonso M. Gañán-Calvo +6 more
TL;DR: A method to generate steady coaxial jets of immiscible liquids with diameters in the range of micrometer/nanometer size is reported, which has produced monodisperse capsules with diameter varying between 10 and 0.15 micrometers, depending on the running parameters.
Journal ArticleDOI
Classification of the Modes of Ehd Spraying
Anatol Jaworek,Andrzej Krupa +1 more
TL;DR: In this paper, the authors classified electrohydrodynamic (EHD) spraying and their classification according to geometric criteria, based on the forms of meniscus and jet, and the mechanism of the disintegration of the jet into droplets (type of instability).
Journal ArticleDOI
Upward needleless electrospinning of multiple nanofibers
Alexander L. Yarin,Eyal Zussman +1 more
TL;DR: In this article, a two-layer system, with the lower layer being a ferromagnetic suspension and the upper layer a polymer solution, is subject to a normal magnetic field provided by a permanent magnet or a coil.
Journal ArticleDOI
Precise control of PLG microsphere size provides enhanced control of drug release rate.
TL;DR: Mixing of uniform microspheres, as well as control of microsphere size distribution, may provide an improved methodology to tailor small-molecule drug-release kinetics from simple, biodegradable-polymer microparticles.