PHYLUCE is a software package for the analysis of conserved genomic loci.

TLDR: PHYLUCE is an efficient and easy-to-install software package that accomplishes targeted enrichment of conserved and ultraconserved genomic elements across hundreds of taxa and thousands of enriched loci.

Abstract: Summary: Targeted enrichment of conserved and ultraconserved genomic elements allows universal collection of phylogenomic data from hundreds of species at multiple time scales ( 300 Ma). Prior to downstream inference, data from these types of targeted enrichment studies must undergo preprocessing to assemble contigs from sequence data; identify targeted, enriched loci from the off-target background data; align enriched contigs representing conserved loci to one another; and prepare and manipulate these alignments for subsequent phylogenomic inference. PHYLUCE is an efficient and easy-to-install software package that accomplishes these tasks across hundreds of taxa and thousands of enriched loci. Availability and Implementation: PHYLUCE is written for Python 2.7. PHYLUCE is supported on OSX and Linux (RedHat/CentOS) operating systems. PHYLUCE source code is distributed under a BSD-style license from https://www.github.com/faircloth-lab/phyluce/. PHYLUCE is also available as a package (https://binstar.org/faircloth-lab/phyluce) for the Anaconda Python distribution that installs all dependencies, and users can request a PHYLUCE instance on iPlant Atmosphere (tag: phyluce). The software manual and a tutorial are available from http://phyluce.readthedocs.org/en/latest/ and test data are available from doi: 10.6084/m9.figshare.1284521. Contact: brant@faircloth-lab.org Supplementary information: Supplementary data are available at Bioinformatics online.

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The copyright holder for this preprint (which was notthis version posted October 30, 2015. ; https://doi.org/10.1101/027904doi: bioRxiv preprint

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.CC-BY 4.0 International licensea
certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under
The copyright holder for this preprint (which was notthis version posted October 30, 2015. ; https://doi.org/10.1101/027904doi: bioRxiv preprint