Journal ArticleDOI
Plasma needle for in vivo medical treatment: recent developments and perspectives
Eva Stoffels,I.E. Kieft,R.E.J. Sladek,L J M van den Bedem,E.P. van der Laan,M Maarten Steinbuch +5 more
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TLDR
The hitherto unravelled facts on the interactions of a cold atmospheric plasma with living cells and tissues are described.Abstract:
In this paper we describe the hitherto unravelled facts on the interactions of a cold atmospheric plasma with living cells and tissues. A specially designed source, plasma needle, is a low-power discharge, which operates under the threshold of tissue damage. When applied properly, the needle does not cause fatal cell injury which would result in cell death (necrosis). Instead, it allows precise and localized cell removal by means of the so-called cell detachment. In addition, plasma can be used for bacterial disinfection. Because of mild treatment conditions, plasma disinfection can be performed in vivo, e.g. on wounds and dental cavities. Presently, one strives to obtain a better control of the operating device. Therefore, plasma has been characterized using a variety of diagnostics, and a smart system has been designed for the positioning of the device with respect to the treated surface.read more
Citations
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Journal ArticleDOI
Experimental and simulation analysis of dielectric barrier discharge based pulsed cold atmospheric pressure plasma jet
TL;DR: In this article, an experimental and simulation investigation has been carried out for the characterization of the dielectric barrier discharge based cold atmospheric pressure plasma jet (C-APPJ) for a unique geometry in which argon gas is used at different flow rates along with pulsed DC supply at different frequencies.
Journal ArticleDOI
Numerical simulation of an atmospheric pressure RF-driven plasma needle and heat transfer to adjacent human skin using COMSOL.
TL;DR: A model is presented, which is capable of predicting the skin temperature during a treatment with a radio frequency driven plasma needle, and provides maximum application times for different power depositions in order to avoid reaching critical skin temperatures.
Journal ArticleDOI
Charge-Transfer Processes in Warm Dense Matter: Selective Spectral Filtering for Laser-Accelerated Ion Beams.
TL;DR: This work investigates, both experimentally and theoretically, how the spectral distribution of laser accelerated carbon ions can be filtered by charge exchange processes in a double foil target setup and determines how the efficiency of charge transfer processes can be manipulated by controlling the ionization degree of the transfer matter.
Journal ArticleDOI
Gas flow dependence of atmospheric pressure plasma needle discharge characteristics
TL;DR: In this article, a two-dimensional coupled model of neutral gas flow and plasma dynamics is presented to explain the gas flow dependence of discharge characteristics in helium plasma needle at atmospherics pressure.
Journal ArticleDOI
Bacteria inactivation by atmospheric pressure plasma jet treatment
M. Pedroni,Stefano Morandi,Tiziana Silvetti,A. Cremona,G. Gittini,Antonio Nardone,F. Pallotta,Milena Brasca,Espedito Vassallo +8 more
TL;DR: In this article, a home-made atmospheric pressure plasma jet device was built and the effects of air plasma treatments on the inactivation of pure bacterial culture (Escherichia coli ATCC 8739) deposited onto the surface of agar plates were investigated.
References
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Book
Feedback Control of Dynamic Systems
TL;DR: This introductory book provides an in-depth, comprehensive treatment of a collection of classical and state-space approaches to control system design and ties the methods together so that a designer is able to pick the method that best fits the problem at hand.
Journal ArticleDOI
Low-temperature sterilization using gas plasmas: a review of the experiments and an analysis of the inactivation mechanisms
TL;DR: In this paper, a review of the literature on plasma sterilization is presented, where three basic mechanisms are involved in the plasma inactivation of microorganisms: (a) direct destruction by UV irradiation of the genetic material of micro organisms; (b) erosion of the microorganisms atom by atom, through intrinsic photodesorption by ultraviolet irradiation to form volatile compounds combining atoms intrinsic to the micro organisms.
Journal ArticleDOI
Nonthermal decontamination of biological media by atmospheric-pressure plasmas: review, analysis, and prospects
TL;DR: A review of various works on the germicidal effects of atmospheric pressure, "cold" plasmas, is presented in this article, where nonequilibrium discharge devices discussed in this review, which have been used in biological applications by various investigators, are the corona discharge, diffuse dielectric-barrier discharge, resistive barrier discharge, and the atmospheric-pressure plasma jet.
Journal ArticleDOI
Plasma needle: a non-destructive atmospheric plasma source for fine surface treatment of (bio)materials
TL;DR: In this paper, a non-thermal plasma source (plasma needle) generated under atmospheric pressure by means of radiofrequency excitation has been characterized, which can be applied on organic materials, also in watery environment, without causing thermal/electric damage to the surface.
Patent
Electrosurgical method and apparatus for initiating an electrical discharge in an inert gas flow
TL;DR: An electrosurgical method and apparatus for coagulating by fulguration where the electrical discharge is established through a formation of flowing inert gas where the formation may either be a diffuse blanket of the flowing gas or a well defined column thereof is described in this paper.