Journal ArticleDOI
Room-temperature atmospheric pressure plasma plume for biomedical applications
Mounir Laroussi,Xinpei Lu +1 more
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TLDR
In this paper, the authors present a device that is capable of generating a cold plasma plume several centimeters in length and exhibits low power requirements as shown by its currentvoltage characteristics.Abstract:
As low-temperature nonequilibrium plasmas come to play an increasing role in biomedical applications, reliable and user-friendly sources need to be developed. These plasma sources have to meet stringent requirements such as low temperature (at or near room temperature), no risk of arcing, operation at atmospheric pressure, preferably hand-held operation, low concentration of ozone generation, etc. In this letter, we present a device that meets exactly such requirements. This device is capable of generating a cold plasma plume several centimeters in length. It exhibits low power requirements as shown by its current-voltage characteristics. Using helium as a carrier gas, very little ozone is generated and the gas temperature, as measured by emission spectroscopy, remains at room temperature even after hours of operations. The plasma plume can be touched by bare hands and can be directed manually by a user to come in contact with delicate objects and materials including skin and dental gum without causing any heating or painful sensation.read more
Citations
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Journal ArticleDOI
Applied Plasma Medicine
Gregory Fridman,Gary Friedman,Alexander Gutsol,Anatoly B. Shekhter,Victor N. Vasilets,Alexander Fridman +5 more
TL;DR: Non-equilibrium plasmas will be shown to be non-destructive to tissue, safe, and effective in inactivation of various parasites and foreign organisms.
Journal ArticleDOI
The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology
TL;DR: The importance of ROS and RNS to plant biology has been relatively little appreciated in the plasma biomedicine community, but it appears that there are opportunities for useful applications of plasmas in this area as well.
Journal ArticleDOI
Reactive species in non-equilibrium atmospheric-pressure plasmas: Generation, transport, and biological effects
Xinpei Lu,Xinpei Lu,George V. Naidis,Mounir Laroussi,Stephan Reuter,David B. Graves,Ken Ostrikov +6 more
TL;DR: In this paper, the most important mechanisms of generation and transport of the key species in the plasmas of atmospheric-pressure plasma jets and other non-equilibrium atmospheric pressure plasms are introduced and examined from the viewpoint of their applications in plasma hygiene and medicine and other relevant fields.
Journal ArticleDOI
Antimicrobial strategies centered around reactive oxygen species - bactericidal antibiotics, photodynamic therapy and beyond
Fatma Vatansever,Wanessa C.M.A. de Melo,Wanessa C.M.A. de Melo,Pinar Avci,Pinar Avci,Daniela Vecchio,Magesh Sadasivam,Magesh Sadasivam,Asheesh Gupta,Asheesh Gupta,Rakkiyappan Chandran,Rakkiyappan Chandran,Mahdi Karimi,Mahdi Karimi,Nivaldo Antonio Parizotto,Rui Yin,Rui Yin,George P. Tegos,Michael R. Hamblin,Michael R. Hamblin +19 more
TL;DR: Antioxidant defenses against ROS in microbial cells and the use of ROS by antimicrobial host defense systems are covered and reactive nitrogen species and related therapeutics, such as acidified nitrite and nitric oxide-releasing nanoparticles are covered.
Journal ArticleDOI
Plasmas for medicine
TL;DR: The aim of the new research field of plasma medicine is the exploitation of a much more differentiated interaction of specific plasma components with specific structural as well as functional elements or functionalities of living cells.
References
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Journal ArticleDOI
Nonthermal decontamination of biological media by atmospheric-pressure plasmas: review, analysis, and prospects
TL;DR: A review of various works on the germicidal effects of atmospheric pressure, "cold" plasmas, is presented in this article, where nonequilibrium discharge devices discussed in this review, which have been used in biological applications by various investigators, are the corona discharge, diffuse dielectric-barrier discharge, resistive barrier discharge, and the atmospheric-pressure plasma jet.
Journal ArticleDOI
Plasma needle: a non-destructive atmospheric plasma source for fine surface treatment of (bio)materials
TL;DR: In this paper, a non-thermal plasma source (plasma needle) generated under atmospheric pressure by means of radiofrequency excitation has been characterized, which can be applied on organic materials, also in watery environment, without causing thermal/electric damage to the surface.
Journal ArticleDOI
Excitation of dielectric barrier discharges by unipolar submicrosecond square pulses
Shuhai Liu,Manfred Neiger +1 more
TL;DR: In this paper, a temporally dynamic model for diffuse DBDs is introduced, from which equations were derived which allowed the calculation of internal electrical quantities in the discharge gap from measured external electrical quantities.
Journal ArticleDOI
Power consideration in the pulsed dielectric barrier discharge at atmospheric pressure
TL;DR: In this article, a specially designed, dielectric barrier discharge based diffuse pulsed discharge and its electrical characteristics are described. But the authors do not specify the electrical characteristics of the discharge.
Journal ArticleDOI
Development and application of a microbeam plasma generator
Hideomi Koinuma,H. Ohkubo,Takuya Hashimoto,Kiyoto Inomata,Tadashi Shiraishi,Akiharu Miyanaga,Shigenori Hayashi +6 more
TL;DR: In this article, a microbeam plasma was successfully generated by using an originally designed capacitively coupled rf plasma reactor which was composed of a needle cathode (1 mm φ), a cylindrical anode (3 mmπ), and a quartz tubing inserted between the cathode and anode.