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Polysaccharide-based aerogels—Promising biodegradable carriers for drug delivery systems

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TLDR
This review focuses on the state-of-the-art of the production of polysaccharide-based aerogels with emphasis on the influence of processing parameters on the resulting end material properties.
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This article is published in Carbohydrate Polymers.The article was published on 2011-10-15. It has received 594 citations till now. The article focuses on the topics: Drug carrier & Drug delivery.

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Microfluidic-assisted synthesis of hemispherical and discoidal chitosan microparticles at an oil/water interface.

TL;DR: This study reports a facile method for the synthesis of hemispherical and discoidal chitosan microparticles by a combination of microfluidic technology and gelation strategy at an oil/water interface using a simple, low‐cost and high‐throughput process.
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Preparation and characterization of polysaccharide - silica hybrid aerogels

TL;DR: It is shown, that the addition of silica to pectin, xanthan, alginate and guar significantly improved their structural properties, primarily seen in the drastic increase of the surface area.
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Polysaccharide-Based Edible Gels as Functional Ingredients: Characterization, Applicability, and Human Health Benefits

TL;DR: The correlation between PEG consumption and polysaccharides properties for human health (e.g., intestinal microecology, “bridge effect” in obesity, gut microbiota) are critically discussed for the first time.
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Role of rheological properties on physical chitosan aerogels obtained by supercritical drying

TL;DR: Aerogels stress-strain responses were also successfully fitted using a hyperelastic equation with three adjustable parameters (Yeoh), showing that this type of models must be taken into account when large stresses are studied.
References
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Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

A review of chitin and chitosan applications

TL;DR: Chitin is the most abundant natural amino polysaccharide and is estimated to be produced annually almost as much as cellulose, and recent progress in chitin chemistry is quite noteworthy as mentioned in this paper.
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Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Biological interactions between polysaccharides and divalent cations: The egg‐box model

TL;DR: It is shown that spedfic binding of divalent cations to a polysaechafide polyelectro]ym, leading firm cohesion between the chains, can cause characteristic effects in the c~rcutar diehroism spectrum which are understandabb in terms of modem theo~, [ l ].
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The Design of Scaffolds for Use in Tissue Engineering. Part I. Traditional Factors

TL;DR: The authors analyze the factors necessary to enhance the design and manufacture of scaffolds for use in tissue engineering in terms of materials, structure, and mechanical properties and review the traditional scaffold fabrication methods.
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