Journal ArticleDOI
Polysaccharide-based aerogels—Promising biodegradable carriers for drug delivery systems
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TLDR
This review focuses on the state-of-the-art of the production of polysaccharide-based aerogels with emphasis on the influence of processing parameters on the resulting end material properties.About:
This article is published in Carbohydrate Polymers.The article was published on 2011-10-15. It has received 594 citations till now. The article focuses on the topics: Drug carrier & Drug delivery.read more
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Jet Cutting Technique for the Production of Chitosan Aerogel Microparticles Loaded with Vancomycin
Clara López-Iglesias,Joana Barros,Inés Ardao,Pavel Gurikov,Fernando J. Monteiro,Irina Smirnova,Carmen Alvarez-Lorenzo,Carlos A. García-González +7 more
TL;DR: In this work, the technological combination of jet cutting and supercritical drying of gels was assessed to produce chitosan aerogel microparticles loaded with vancomycin HCl (antimicrobial agent) for wound healing purposes, which had excellent textural properties, absorbed high amounts of exudate, and controlled the release of vancomysin HCl, providing sustained antimicrobial activity.
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Transparent and flame retardant cellulose/aluminum hydroxide nanocomposite aerogels
TL;DR: In this article, aluminum hydroxide (AH) nanoparticles were incorporated into cellulose gels via in-situ sol-gel synthesis and following supercritical CO2 drying, and the resulting nanocomposite aerogels exhibited good transparency and excellent mechanical properties.
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Effect of starch xero‐ and aerogels preparation on the supercritical CO2 impregnation of thymol
TL;DR: In this article, the supercritical solvent impregnation (SSI) technique has been used to test the incorporation of thymol into starch gels, and the results indicated the great potential of the corn starch xerogel for commercial use as a carrier in pharmaceuticals and nutraceuticals.
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Matrix systems for oral drug delivery: Formulations and drug release.
Gábor Vasvári,József Kalmár,Péter Veres,Miklós Vecsernyés,Ildikó Bácskay,Pálma Fehér,Zoltán Ujhelyi,Ádám Haimhoffer,Ágnes Rusznyák,Ferenc Fenyvesi,Judit Váradi +10 more
TL;DR: Main drug release mechanisms are detailed and reviewed to support rational design in pharmaceutical technology and manufacturing considering the fact that R&D members of the industry are forced to obtain knowledge about excipients and methods pros and cons.
Journal ArticleDOI
Sustainable Approach for Cellulose Aerogel Preparationfrom the DBU–CO 2 Switchable Solvent
Kelechukwu N. Onwukamike,Kelechukwu N. Onwukamike,Laurine Lapuyade,Laurence Maillé,Stéphane Grelier,Etienne Grau,Henri Cramail,Michael A. R. Meier +7 more
TL;DR: A sustainable and easy approach for the preparation of cellulose-based aerogels from the DBU-CO2 switchable solvent system via a solubilization and coagulation approach followed by freeze-drying is reported in this article.
References
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A review of chitin and chitosan applications
TL;DR: Chitin is the most abundant natural amino polysaccharide and is estimated to be produced annually almost as much as cellulose, and recent progress in chitin chemistry is quite noteworthy as mentioned in this paper.
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Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Biological interactions between polysaccharides and divalent cations: The egg‐box model
TL;DR: It is shown that spedfic binding of divalent cations to a polysaechafide polyelectro]ym, leading firm cohesion between the chains, can cause characteristic effects in the c~rcutar diehroism spectrum which are understandabb in terms of modem theo~, [ l ].
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The Design of Scaffolds for Use in Tissue Engineering. Part I. Traditional Factors
TL;DR: The authors analyze the factors necessary to enhance the design and manufacture of scaffolds for use in tissue engineering in terms of materials, structure, and mechanical properties and review the traditional scaffold fabrication methods.