Journal ArticleDOI
Regulation of protrusion shape and adhesion to the substratum during chemotactic responses of mammalian carcinoma cells.
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The results suggest that, although adhesive contacts are not necessary for lamellipod extension, they play a role in stabilizing the protrusion as well as in the control of its final shape and amplitude.About:
This article is published in Experimental Cell Research.The article was published on 1998-06-15. It has received 158 citations till now.read more
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Patterning proteins and cells using soft lithography
TL;DR: This review describes the pattering of proteins and cells using a non-photolithographic microfabrication technology, which consists of a set of related techniques, each of which uses stamps or channels fabricated in an elastomeric ('soft') material for pattern transfer.
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Unconventional Methods for Fabricating and Patterning Nanostructures.
TL;DR: Lithography with Neutral Metastable Atoms 1838 4.1.
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A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors.
Jeffrey B. Wyckoff,Weigang Wang,Elaine Y. Lin,Yarong Wang,Fiona J. Pixley,E. Richard Stanley,Thomas Graf,Jeffrey W. Pollard,Jeffrey E. Segall,John S. Condeelis +9 more
TL;DR: This work provides the first direct evidence for a synergistic interaction between macrophages and tumor cells during cell migration in vivo and indicates a mechanism for how macrophage may contribute to metastasis.
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Proteins of the ADF/Cofilin Family: Essential Regulators of Actin Dynamics
TL;DR: Although vertebrate ADF/cofilins contain a nuclear localization sequence, they are usually concentrated in regions containing dynamic actin pools, such as the leading edge of migrating cells and neuronal growth cones.
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Intravital imaging of cell movement in tumours
TL;DR: Multiphoton microscopy has been developed for in vivo imaging and, using this technique, scientists are beginning to understand how invasive tumour cells move.
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Journal ArticleDOI
Integrins: versatility, modulation, and signaling in cell adhesion.
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Geometric control of cell life and death.
TL;DR: Human and bovine capillary endothelial cells were switched from growth to apoptosis by using micropatterned substrates that contained extracellular matrix-coated adhesive islands of decreasing size to progressively restrict cell extension.
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Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
Catherine D. Nobes,Alan Hall +1 more
TL;DR: It is reported here that cdc42, another member of the rho family, triggers the formation of a third type of actin-based structure found at the cell periphery, filopodia, in addition to stress fibers, and rho controls the assembly of focal adhesion complexes.
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Cell Migration: A Physically Integrated Molecular Process
TL;DR: The authors are grateful for financial support from the National Institutes of Health (grants GM23244 and GM53905), and to very helpful comments on the manuscript from Elliot Elson, Vlodya Gelfand, Paul Matsudaira, Julie Theriot, and Sally Zigmond.
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Features of gold having micrometer to centimeter dimensions can be formed through a combination of stamping with an elastomeric stamp and an alkanethiol ‘‘ink’’ followed by chemical etching
Amit Kumar,George M. Whitesides +1 more
TL;DR: In this paper, a technique for patterning a self-assembled monolayer (SAM) on a gold substrate using an elastomer stamp was described, followed by selective etching in an aqueous, basic solution of cyanide ion and dissolved dioxygen (1M KOH, 0.1 M KCN).