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Open AccessJournal ArticleDOI

Relevance of diagnostic investigations in patients with uveitis: Retrospective cohort study on 300 patients.

TLDR
Investigation of factors associated with abnormal investigations might improve the optimal diagnostic workup adapted to each patient of uveitis.
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This article is published in Autoimmunity Reviews.The article was published on 2017-05-01 and is currently open access. It has received 38 citations till now. The article focuses on the topics: Uveitis & Retrospective cohort study.

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Journal ArticleDOI

Autoimmunity, Autoinflammation, and Infection in Uveitis.

TL;DR: It is shown that the possibility that a dysregulated microbiome might generate T cells that cause immune-mediated ocular inflammation has now been demonstrated experimentally and is proposed within a unifying concept for the pathogenesis of uveitis.
Journal ArticleDOI

Uveitis: Diagnostic work-up. A literature review and recommendations from an expert committee.

TL;DR: Recommendations were developed by a multidisciplinary panel of 14 experts, including internists, ophthalmologists, and rheumatologists, based on a review of the literature and the results of the ULISSE study, which was the first prospective study to assess the efficacy of a standardized strategy for the etiologic diagnosis of uveitis.
Journal ArticleDOI

Small-fiber neuropathy definition, diagnosis, and treatment

TL;DR: In the last 30 years, improvement of diagnostic methods enabled routine evaluation of small A-delta and C nerve fibers impairment, which results with the clinical condition known as a small-fiber neuropathy (SFN) as mentioned in this paper.
Journal ArticleDOI

Uveitis: Autoimmunity… and beyond.

TL;DR: One of the largest cohorts of consecutive uveitis patients referred to a department of internal medicine is described, highlighting the need for a multidisciplinary approach in order to reduce the diagnostic delay.
References
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Journal ArticleDOI

The European spondylarthropathy study group preliminary criteria for the classification of spondylarthropathy

TL;DR: The proposed classification criteria for spondylarthropathy are easy to apply in clinical practice and performed well in all 7 participating centers and are regarded as preliminary until they have been further evaluated in other settings.
Journal ArticleDOI

The International Criteria for Behçet's Disease (ICBD): A collaborative study of 27 countries on the sensitivity and specificity of the new criteria

TL;DR: Behçet's disease (BD) is a chronic, relapsing, inflammatory vascular disease with no pathognomonic test.
Journal ArticleDOI

Incidence and prevalence of uveitis in Northern California: The Northern California Epidemiology of Uveitis Study

TL;DR: In this largest population-based uveitis study in the United States to date, the incidence of uveritis was approximately 3 times that of previous U.S. estimates and increased with the increasing age of patients.
Related Papers (5)
Frequently Asked Questions (6)
Q1. What have the authors contributed in "Pertinence des examens complémentaires au cours du bilan étiologique des uvéites: étude rétrospective de 300 patients" ?

The authors aimed to evaluate the relevance of diagnostic investigations for the etiological diagnosis of uveitis. Chest CT-scan was suggestive of sarcoidosis in 29 %. Bronchoscopy showed granuloma in 11 % while alveolar lymphocytosis suggestive of sarcoidosis was reported in 27 %. 

Les patients avec du granulome sur les biopsies bronchiques avaient toujours des anomalies au scanner thoracique (adénopathies médiastinohilaires et/ou infiltrats parenchymateux) tandis que 14 patients (31%) avec une lymphocytose alvéolaire avaient un scanner thoracique normal. 

A l’issue de ces explorations, le diagnostic d’uvéite d’origine inflammatoire a été posé chez 104 patients (35%), incluant une sarcoïdose dans 22% des cas (parmi lesquels 32 sarcoïdoses définies, 30 présumées, et 4 probables), une maladie de Behçet dans 5% des cas, et une spondylarthropathie dans 5% des cas. 

Les uvéites secondaires à une pathologie ophtalmologique pure, compliquant une pathologie déjà connue antérieurement, ou secondaires à une pathologie infectieuse évidente (herpes, syphilis, toxoplasmose etc..) ont été exclues de l’analyse. 

La présence de granulome était toujours associée à des anomalies au TDM, tandis que 31% des patients avec une lymphocytose alvéolaire avaient un TDM normal. 

2.8 Traitement et évolution des uvéitesCent-cinquante patients (50%) ont été traités avec un traitement systémique, incluant 77% des patients avec un diagnostic étiologique identifié contre 23% avec une uvéite d’origine indéterminée (P<0,0001).