Journal ArticleDOI
Rotation of single live mammalian cells using dynamic holographic optical tweezers
TLDR
The method enables a complete 360° rotation of live single mammalian cells with spherical or near-to spherical shape in 3D space, and represents a useful tool suitable for the single cell analysis field, including tomographic imaging.About:
This article is published in Optics and Lasers in Engineering.The article was published on 2017-05-01. It has received 41 citations till now. The article focuses on the topics: Optical tweezers.read more
Citations
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Journal ArticleDOI
Out-of-Plane Rotation Control of Biological Cells With a Robot-Tweezers Manipulation System for Orientation-Based Cell Surgery
TL;DR: The dynamic model of cell out-of-plane orientation control is formulated by using the T-matrix approach and produces impactful benefits to cell surgery applications such as nucleus transplantation and organelle biopsy in precision medicine.
Journal ArticleDOI
Optically driven full-angle sample rotation for tomographic imaging in digital holographic microscopy.
TL;DR: The proposed approach shows that an entire symmetric spectrum can be acquired for tomographic reconstruction without the missing apple core problem as in traditional sample-rotation schemes.
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Integrated dual-tomography for refractive index analysis of free-floating single living cell with isotropic superresolution
TL;DR: This is the first study focusing on the development of an integrated dual-tomographic (IDT) imaging system for RI measurement of an unlabelled free-floating single living cell with an isotropic superresolution by combining the spatial frequencies of full-angle specimen rotation with those of beam rotation.
Journal ArticleDOI
Simultaneous optical trapping and imaging in the axial plane: a review of current progress.
Yansheng Liang,Shaohui Yan,Zhaojun Wang,Runze Li,Yanan Cai,Minru He,Baoli Yao,Ming Lei,Ming Lei +8 more
TL;DR: An optical tweezer system is developed that allows for simultaneous optical trapping and imaging technique and the potential applications are suggested to several fields, including optical pulling, longitudinal optical binding, tomographic phase microscopy and superresolution microscopy.
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Lab-on-a-chip technologies for the single cell level: Separation, analysis, and diagnostics
TL;DR: An overview of the field in general and the most notable developments of the last five years is given, along with potentials, shortfalls, and an outlook on future developments, especially in respect to the funding landscape and the field-application of these chips.
References
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Journal ArticleDOI
Observation of a single-beam gradient force optical trap for dielectric particles
TL;DR: Optical trapping of dielectric particles by a single-beam gradient force trap was demonstrated for the first reported time, confirming the concept of negative light pressure due to the gradient force.
Journal ArticleDOI
Optical trapping and manipulation of single cells using infrared laser beams
TL;DR: The use of infrared (IR) light is used to make much improved laser traps with significantly less optical damage to a variety of living cells, and new manipulative techniques using IR light are capable of producing large forces under damage-free conditions and improve the prospects for wider use of optical manipulation techniques in microbiology.
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Optical Trapping and Manipulation of Viruses and Bacteria
Arthur Ashkin,J. M. Dziedzic +1 more
TL;DR: Trapping and manipulation of single live motile bacteria and Escherichia coli bacteria were demonstrated in a high-resolution microscope at powers of a few milliwatts.
Journal ArticleDOI
Tweezers with a twist
Miles J. Padgett,Richard Bowman +1 more
TL;DR: The fact that light carries both linear and angular momentum is well-known to physicists as discussed by the authors, and one application of the linear momentum of light is for optical tweezers, in which the refraction of a laser beam through a particle provides a reaction force that draws the particle towards the centre of the beam.
Journal ArticleDOI
Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence.
Jochen Guck,Stefan Schinkinger,Stefan Schinkinger,Bryan Lincoln,Bryan Lincoln,Falk Wottawah,Falk Wottawah,Susanne Ebert,Maren Romeyke,Dominik Lenz,Harold M. Erickson,Revathi Ananthakrishnan,Revathi Ananthakrishnan,Daniel Mitchell,Josef A. Käs,Josef A. Käs,Sydney Ulvick,Curt Bilby +17 more
TL;DR: It is found that optical deformability is sensitive enough to monitor the subtle changes during the progression of mouse fibroblasts and human breast epithelial cells from normal to cancerous and even metastatic state, and suggests using optical deformable as an inherent cell marker for basic cell biological investigation and diagnosis of disease.