Journal ArticleDOI
Safety Evaluation and Risk Assessment of the Herbicide Roundup and Its Active Ingredient, Glyphosate, for Humans
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TLDR
It was concluded that the use of Roundup herbicide does not result in adverse effects on development, reproduction, or endocrine systems in humans and other mammals, and glyphosate is noncarcinogenic.About:
This article is published in Regulatory Toxicology and Pharmacology.The article was published on 2000-04-01. It has received 742 citations till now. The article focuses on the topics: Aminomethylphosphonic acid & Glyphosate.read more
Citations
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Journal ArticleDOI
Glyphosate: a once-in-a-century herbicide.
TL;DR: The use of this virtually ideal herbicide is now being threatened by the evolution of glyphosate-resistant weeds, and adoption of resistance management practices will be required to maintain the benefits of glyphosate technologies for future generations.
Journal ArticleDOI
Chemical Pesticides and Human Health: The Urgent Need for a New Concept in Agriculture.
P. Nicolopoulou-Stamati,Sotirios Maipas,Chrysanthi Kotampasi,Panagiotis J. Stamatis,Luc Hens +4 more
TL;DR: It is more obvious than ever that the society needs the implementation of a new agricultural concept regarding food production, which is safer for man and the environment, and to this end, steps such as the declaration of Nyéléni have been taken.
Book ChapterDOI
Ecotoxicological Risk Assessment for Roundup ® Herbicide
TL;DR: Glyphosate-based weed control products are among the most widely used broad-spectrum herbicides in the world and have been extensively investigated for their potential to produce adverse effects in nontarget organisms as discussed by the authors.
Journal ArticleDOI
Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement
John Peterson Myers,Michael Antoniou,Bruce Blumberg,Lynn Carroll,Theo Colborn,Lorne G. Everett,Michael Hansen,Philip J. Landrigan,Bruce P. Lanphear,Robin Mesnage,Laura N. Vandenberg,Frederick S. vom Saal,Wade V. Welshons,Charles Benbrook +13 more
TL;DR: GBHs are the most heavily applied herbicide in the world and usage continues to rise; Worldwide, GBHs often contaminate drinking water sources, precipitation, and air, especially in agricultural regions and regulatory estimates of tolerable daily intakes for glyphosate in the United States and European Union are based on outdated science.
Journal ArticleDOI
Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines.
Céline Gasnier,Coralie Dumont,Nora Benachour,Emilie Clair,Marie-Christine Chagnon,Gilles-Eric Séralini +5 more
TL;DR: A real cell impact of glyphosate-based herbicides residues in food, feed or in the environment has thus to be considered, and their classifications as carcinogens/mutagens/reprotoxics is discussed.
References
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Book
Risk Assessment in the Federal Government: Managing the Process
TL;DR: The risk assessment/risk management knowledge representation was the capacity that it granted to the administrators of the EPA to design a joint decision-making process involving the various programmatic and functional offices of the agency and assembling the expertise and specific conceptions of uncertainty of toxicologists, economists, and policy analysts.
Journal ArticleDOI
Chromosomal translocations in human cancer.
TL;DR: Fusion proteins formed after chromosomal translocations are common in a range of tumour types; these are unique tumour antigens and are therefore potential targets for therapy design.
Journal ArticleDOI
Detergent components in sewage effluent are weakly oestrogenic to fish: An in vitro study using rainbow trout (Oncorhynchus mykiss) hepatocytes
Susan Jobling,John P. Sumpter +1 more
TL;DR: Simultaneous exposure of the hepatocytes to Tamoxifen and effective doses of representative compounds caused an inhibition of the oestrogenic effect in all cases, suggesting that the action of these compounds is mediated by the Oestradiol receptor.