Journal ArticleDOI
Salivary cortisol as a biomarker in stress research.
TLDR
The present paper addresses several psychological and biological variables, which may account for such dissociations, and aims to help researchers to rate the validity and psychobiological significance of salivary cortisol as an HPAA biomarker of stress in their experiments.About:
This article is published in Psychoneuroendocrinology.The article was published on 2009-02-01. It has received 1472 citations till now. The article focuses on the topics: Adrenocorticotropic hormone.read more
Citations
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Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge.
TL;DR: This overview demonstrates the role of age and gender, endogenous and exogenous sex steroid levels, pregnancy, lactation and breast-feeding, smoking, coffee and alcohol consumption as well as dietary energy supply in salivary cortisol responses to acute stress.
Journal ArticleDOI
Measuring stress in wildlife: techniques for quantifying glucocorticoids
Michael J. Sheriff,Michael J. Sheriff,Ben Dantzer,Brendan Delehanty,Rupert Palme,Rudy Boonstra +5 more
TL;DR: An overview of the four main biological samples that have been utilized, their advantages and disadvantages for use with wildlife, and some of the background and pitfalls that users must consider in interpreting their results are given.
Journal ArticleDOI
Assessment of the cortisol awakening response: Expert consensus guidelines.
Tobias Stalder,Clemens Kirschbaum,Brigitte M. Kudielka,Emma K. Adam,Jens C. Pruessner,Stefan Wüst,Samantha Dockray,Nina Smyth,Phil Evans,Dirk H. Hellhammer,Robert Miller,Mark Wetherell,Sonia J. Lupien,Angela Clow +13 more
TL;DR: Consensus guidelines are presented on central aspects of CAR assessment, including objective control of sampling accuracy/adherence, participant instructions, covariate accounting, sampling protocols, quantification strategies as well as reporting and interpreting of CAR data.
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The influence of urban green environments on stress relief measures: A field experiment
TL;DR: In this paper, the authors investigated the psychological and physiological effects of short-term visits to urban nature environments, and found that the salivary cortisol level decreased in a similar fashion in all three urban environments during the experiment.
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The cortisol awakening response: more than a measure of HPA axis function.
TL;DR: Evidence is presented for reduced adrenal sensitivity to rising levels of ACTH in the pre-awakening period, mediated by an extra-pituitary pathway to the adrenal from the suprachiasmatic nucleus (SCN).
References
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Journal ArticleDOI
Sex specific associations between common glucocorticoid receptor gene variants and hypothalamus-pituitary-adrenal axis responses to psychosocial stress
Robert Kumsta,Sonja Entringer,Jan W. Koper,Elisabeth F.C. van Rossum,Dirk H. Hellhammer,Stefan Wüst +5 more
TL;DR: Significant sex specific associations between GR gene polymorphisms and HPA axis responses to psychosocial stress as well as GC sensitivity support the relevance of GRGene polymorphisms in Hpa axis regulation.
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Free cortisol awakening responses are influenced by awakening time
Ilona S. Federenko,Stefan Wüst,Dirk H. Hellhammer,Ralph Dechoux,Robert Kumsta,Clemens Kirschbaum +5 more
TL;DR: The present study shows that in a sample with a large range of awakening times, an impact of this variable on the cortisol awakening response can be observed, and suggests that waking up per se is insufficient for adrenocortical stimulation.
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The stability of and intercorrelations among cardiovascular, immune, endocrine, and psychological reactivity.
Sheldon Cohen,Natalie Hamrick,Mario S. Rodriguez,Pamela J. Feldman,Bruce S. Rabin,Stephen B. Manuck +5 more
TL;DR: Stability across sessions for stress-induced increases in anxiety and task engagement, heart rate, blood pressure, norpinephrine, cortisol, natural killer cell cytotoxicity, and numbers of circulating CD3+, CD8+, and CD56+ lymphocytes provided evidence of a unified physiological stress response across these outcomes.
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Cortisol fluctuates with increases and decreases in negative affect
TL;DR: The results suggest that the hypothalamic-pituitary-adrenocortical axis is a dynamic system influenced by changes in negative affect irrespective of the experience of generalized activation.
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Glucocorticoid resistance in chronic asthma : peripheral blood T lymphocyte activation and comparison of the T lymphocyte inhibitory effects of glucocorticoids and cyclosporin A
TL;DR: A total of 37 chronic severe asthmatic patients with documented reversible airways obstruction were classified as glucocorticoid sensitive or resistant according to changes in the FEV1 following a course of oral prednisolone and the phenotype and expression of activation molecules on peripheral blood T lymphocytes from these patients just before the course of prednisole were studied.